Microbiota stability in healthy individuals after single-dose lactulose challenge—A randomized controlled study

• Sandra Y. Wotzka ,

  Contributed equally to this work with: Sandra Y. Wotzka, Markus Kreuzer, Lisa Maier

  Roles Conceptualization, Data curation, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Institute of Microbiology, D-BIOL, ETH Zürich, Zürich, Switzerland

  ⨯
• Markus Kreuzer ,

  Contributed equally to this work with: Sandra Y. Wotzka, Markus Kreuzer, Lisa Maier

  Roles Conceptualization, Data curation, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Institute of Microbiology, D-BIOL, ETH Zürich, Zürich, Switzerland

  ⨯
• Lisa Maier ,

  Contributed equally to this work with: Sandra Y. Wotzka, Markus Kreuzer, Lisa Maier

  Roles Conceptualization, Data curation, Formal analysis, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Institute of Microbiology, D-BIOL, ETH Zürich, Zürich, Switzerland

  ⨯
• Mirjam Zünd ,

  Roles Conceptualization, Data curation, Formal analysis, Writing – review & editing

  * E-mail: wolf-dietrich.hardt@micro.biol.ethz.ch (WDH); shinichi.sunagawa@micro.biol.ethz.ch (SS); benjamin.misselwitz@usz.ch (BM)

  Affiliation Institute of Microbiology, D-BIOL, ETH Zürich, Zürich, Switzerland

  ⨯
• Markus Schlumberger,

  Roles Conceptualization, Formal analysis, Investigation, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Institute of Microbiology, D-BIOL, ETH Zürich, Zürich, Switzerland

  ⨯
• Bidong Nguyen,

  Roles Data curation, Formal analysis, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Institute of Microbiology, D-BIOL, ETH Zürich, Zürich, Switzerland

  ⨯
• Mark Fox,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft

  Affiliation Abdominal Center, Gastroenterology, St. Claraspital, Basel, Switzerland

  ⨯
• Daniel Pohl,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Department of Gastroenterology, University Hospital Zurich (USZ), and Zurich University, Zurich, Switzerland

  ⨯
• Henriette Heinrich,

  Roles Data curation, Methodology, Writing – review & editing

  Affiliations Abdominal Center, Gastroenterology, St. Claraspital, Basel, Switzerland, Department of Gastroenterology, University Hospital Zurich (USZ), and Zurich University, Zurich, Switzerland

  http://orcid.org/0000-0001-6355-0921

  ⨯
• Gerhard Rogler,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Gastroenterology, University Hospital Zurich (USZ), and Zurich University, Zurich, Switzerland

  ⨯
• Luc Biedermann,

  Roles Conceptualization, Investigation, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Gastroenterology, University Hospital Zurich (USZ), and Zurich University, Zurich, Switzerland

  ⨯
• Michael Scharl,

  Roles Conceptualization, Data curation, Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

  Affiliation Department of Gastroenterology, University Hospital Zurich (USZ), and Zurich University, Zurich, Switzerland

  ⨯
• Shinichi Sunagawa ,

  Roles Conceptualization, Data curation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: wolf-dietrich.hardt@micro.biol.ethz.ch (WDH); shinichi.sunagawa@micro.biol.ethz.ch (SS); benjamin.misselwitz@usz.ch (BM)

  ¶‡ These authors also contributed equally to this work.

  Affiliation Institute of Microbiology, D-BIOL, ETH Zürich, Zürich, Switzerland

  ⨯
• Wolf-Dietrich Hardt ,

  Roles Conceptualization, Methodology, Resources, Writing – original draft, Writing – review & editing

  * E-mail: wolf-dietrich.hardt@micro.biol.ethz.ch (WDH); shinichi.sunagawa@micro.biol.ethz.ch (SS); benjamin.misselwitz@usz.ch (BM)

  ¶‡ These authors also contributed equally to this work.

  Affiliation Institute of Microbiology, D-BIOL, ETH Zürich, Zürich, Switzerland

  ⨯
• Benjamin Misselwitz

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: wolf-dietrich.hardt@micro.biol.ethz.ch (WDH); shinichi.sunagawa@micro.biol.ethz.ch (SS); benjamin.misselwitz@usz.ch (BM)

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Gastroenterology, University Hospital Zurich (USZ), and Zurich University, Zurich, Switzerland

  ⨯