CB1 receptor blockade ameliorates hepatic fat infiltration and inflammation and increases Nrf2-AMPK pathway in a rat model of severely uncontrolled diabetes

• Eugene Chang ,

  Contributed equally to this work with: Eugene Chang, Dae-Hee Kim

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Nutritional Science and Food Management, Ewha Womans University, Seoul, Seoul, Republic of Korea

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• Dae-Hee Kim ,

  Contributed equally to this work with: Eugene Chang, Dae-Hee Kim

  Roles Data curation, Investigation, Methodology

  Affiliation Medical Research Institute, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

  ⨯
• Hyekyung Yang,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Medical Research Institute, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

  ⨯
• Da Hyun Lee,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Severance Biomedical Science Institute, Yonsei Biomedical Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea

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• Soo Han Bae ,

  Roles Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: cydoctor@chol.com (CYP); soohanbae@yuhs.ac (SHB)

  Affiliation Severance Biomedical Science Institute, Yonsei Biomedical Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea

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• Cheol-Young Park

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: cydoctor@chol.com (CYP); soohanbae@yuhs.ac (SHB)

  Affiliation Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

  http://orcid.org/0000-0002-9415-9965

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