The relationship between serum hepatitis B virus DNA level and liver histology in patients with chronic HBV infection

Changjiang Liu; Li Wang; Huizhong Xie; Liyuan Zhang; Bingshu Wang; Chun Luo; Suiqun Wang; Mingliang Tang; Zhongbiao Fu; Hailan Ruan; Zhengjin Liu; Ling Wei; Wenyi Yi; Yunqian Xie

doi:10.1371/journal.pone.0206060

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Open Access

Peer-reviewed

Research Article

The relationship between serum hepatitis B virus DNA level and liver histology in patients with chronic HBV infection

Changjiang Liu,

Roles Writing – original draft

Affiliation Department of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China

http://orcid.org/0000-0002-7816-0544

⨯
Li Wang,

Roles Formal analysis

Affiliation Department of Pathology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China
⨯
Huizhong Xie ,

Roles Writing – review & editing

* E-mail: hnxiehuizhong@163.com.

Affiliation Department of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China

http://orcid.org/0000-0002-7477-3327

⨯
Liyuan Zhang,

Roles Data curation

Affiliation Department of Infectious Diseases, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China
⨯
Bingshu Wang,

Roles Validation

Affiliation Department of Pathology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China
⨯
Chun Luo,

Roles Validation

Affiliation Department of Pathology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China
⨯
Suiqun Wang,

Roles Validation

Affiliation Department of Pathology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China
⨯
Mingliang Tang,

Roles Resources

Affiliation Department of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China
⨯
Zhongbiao Fu,

Roles Resources

Affiliation Department of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China
⨯
Hailan Ruan,

Roles Resources

Affiliation Department of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China
⨯
Zhengjin Liu,

Roles Resources

Affiliation Department of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China
⨯
Ling Wei,

Roles Resources

Affiliation Department of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China
⨯
Wenyi Yi,

Roles Resources

Affiliation Department of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China
⨯
Yunqian Xie

Roles Resources

Affiliation Department of Gastroenterology, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China
⨯

The relationship between serum hepatitis B virus DNA level and liver histology in patients with chronic HBV infection

Changjiang Liu,
Li Wang,
Huizhong Xie,
Liyuan Zhang,
Bingshu Wang,
Chun Luo,
Suiqun Wang,
Mingliang Tang,
Zhongbiao Fu,
Hailan Ruan

Published: November 7, 2018
https://doi.org/10.1371/journal.pone.0206060

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Liver fibrosis
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Cirrhosis
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Fibrosis
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Hepatitis B virus
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DNA replication
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Liver diseases
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Biopsy
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Necrosis
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