Oncogenic mutations in IKKβ function through global changes induced by K63-linked ubiquitination and result in autocrine stimulation

• April N. Meyer ,

  Contributed equally to this work with: April N. Meyer, Leandro H. Gallo

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America

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• Leandro H. Gallo ,

  Contributed equally to this work with: April N. Meyer, Leandro H. Gallo

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America

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• Juyeon Ko,

  Roles Investigation, Writing – original draft

  Affiliation Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America

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• Guillermo Cardenas,

  Roles Investigation

  Affiliation Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America

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• Katelyn N. Nelson,

  Roles Investigation, Writing – original draft

  Affiliation Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America

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• Asma Siari,

  Roles Investigation

  Affiliation Université Joseph Fourier Grenoble, Grenoble, France

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• Alexandre R. Campos,

  Roles Data curation, Formal analysis, Investigation, Methodology, Supervision, Visualization

  Affiliation Proteomics Facility, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States of America

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• Thomas C. Whisenant,

  Roles Data curation, Formal analysis, Methodology, Supervision, Visualization

  Affiliation Center for Computational Biology and Bioinformatics, University of California San Diego, La Jolla, California, United States of America

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• Daniel J. Donoghue

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: ddonoghue@ucsd.edu

  Affiliations Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America, Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America

  http://orcid.org/0000-0002-4546-2175

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