Co-localization of plaque macrophages with calcification is associated with a more vulnerable plaque phenotype and a greater calcification burden in coronary target segments as determined by OCT

• Mathias Burgmaier ,

  Contributed equally to this work with: Mathias Burgmaier, Andrea Milzi

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Cardiology, University Hospital of the RWTH Aachen, Aachen, Germany

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• Andrea Milzi ,

  Contributed equally to this work with: Mathias Burgmaier, Andrea Milzi

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Cardiology, University Hospital of the RWTH Aachen, Aachen, Germany

  http://orcid.org/0000-0001-7580-8029

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• Rosalia Dettori,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Cardiology, University Hospital of the RWTH Aachen, Aachen, Germany

  ⨯
• Kathrin Burgmaier,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Pediatrics, University Hospital of Cologne, Cologne, Germany

  ⨯
• Nikolaus Marx,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Cardiology, University Hospital of the RWTH Aachen, Aachen, Germany

  ⨯
• Sebastian Reith

  Roles Conceptualization, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: sreith@ukaachen.de

  Affiliation Department of Cardiology, University Hospital of the RWTH Aachen, Aachen, Germany

  ⨯