A quantitative method for measuring the relationship between an objective endpoint and patient reported outcome measures

• Chul Ahn ,

  Contributed equally to this work with: Chul Ahn, Xin Fang

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Xin Fang ,

  Contributed equally to this work with: Chul Ahn, Xin Fang

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: xin.fang@fda.hhs.gov

  Affiliation Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, Maryland, United States of America

  http://orcid.org/0000-0002-2078-2607

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• Phyllis Silverman ,

  Roles Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Zhiwei Zhang

  Roles Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Statistics, University of California, Riverside, CA, United States of America

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