Absolute CD4+ T cell count overstate immune recovery assessed by CD4+/CD8+ ratio in HIV-infected patients on treatment

Yusnelkis Milanés-Guisado; Alicia Gutiérrez-Valencia; María Trujillo-Rodríguez; Nuria Espinosa; Pompeyo Viciana; Luis Fernando López-Cortés

doi:10.1371/journal.pone.0205777

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Open Access

Peer-reviewed

Research Article

Absolute CD4⁺ T cell count overstate immune recovery assessed by CD4⁺/CD8⁺ ratio in HIV-infected patients on treatment

Yusnelkis Milanés-Guisado ,

Contributed equally to this work with: Yusnelkis Milanés-Guisado, Alicia Gutiérrez-Valencia

Roles Data curation, Formal analysis, Writing – original draft

Affiliation Enfermedades Infecciosas, Microbiología Clínica y Medicina Preventiva. Instituto de Biomedicina de Sevilla/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla. Seville, Spain
⨯
Alicia Gutiérrez-Valencia ,

Contributed equally to this work with: Yusnelkis Milanés-Guisado, Alicia Gutiérrez-Valencia

Roles Data curation, Formal analysis, Writing – original draft

Affiliation Enfermedades Infecciosas, Microbiología Clínica y Medicina Preventiva. Instituto de Biomedicina de Sevilla/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla. Seville, Spain
⨯
María Trujillo-Rodríguez,

Roles Investigation, Methodology

Affiliation Enfermedades Infecciosas, Microbiología Clínica y Medicina Preventiva. Instituto de Biomedicina de Sevilla/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla. Seville, Spain
⨯
Nuria Espinosa,

Roles Investigation

Affiliation Enfermedades Infecciosas, Microbiología Clínica y Medicina Preventiva. Instituto de Biomedicina de Sevilla/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla. Seville, Spain
⨯
Pompeyo Viciana,

Roles Investigation

Affiliation Enfermedades Infecciosas, Microbiología Clínica y Medicina Preventiva. Instituto de Biomedicina de Sevilla/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla. Seville, Spain
⨯
Luis Fernando López-Cortés

Roles Conceptualization, Project administration, Writing – review & editing

* E-mail: luisfernando@lopezcortes.net

Affiliation Enfermedades Infecciosas, Microbiología Clínica y Medicina Preventiva. Instituto de Biomedicina de Sevilla/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla. Seville, Spain

http://orcid.org/0000-0002-3804-3458

⨯

Absolute CD4⁺ T cell count overstate immune recovery assessed by CD4⁺/CD8⁺ ratio in HIV-infected patients on treatment

Yusnelkis Milanés-Guisado,
Alicia Gutiérrez-Valencia,
María Trujillo-Rodríguez,
Nuria Espinosa,
Pompeyo Viciana,
Luis Fernando López-Cortés

Published: October 22, 2018
https://doi.org/10.1371/journal.pone.0205777

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T cells
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Antiretroviral therapy
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Cytotoxic T cells
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Cell enumeration techniques
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HIV infections
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Treatment guidelines
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