High-resolution plasma metabolomics analysis to detect Mycobacterium tuberculosis-associated metabolites that distinguish active pulmonary tuberculosis in humans

• Jeffrey M. Collins ,

  Contributed equally to this work with: Jeffrey M. Collins, Douglas I. Walker

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jmcoll4@emory.edu

  Affiliation Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America

  http://orcid.org/0000-0002-6574-0873

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• Douglas I. Walker ,

  Contributed equally to this work with: Jeffrey M. Collins, Douglas I. Walker

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America

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• Dean P. Jones,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Nestani Tukvadze,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Writing – review & editing

  Affiliation National Center for Tuberculosis and Lung Disease, Tbilisi, Georgia

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• Ken H. Liu,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• ViLinh T. Tran,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Karan Uppal,

  Roles Data curation, Formal analysis, Methodology, Software, Visualization, Writing – review & editing

  Affiliation Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Jennifer K. Frediani,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliation Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, United States of America

  http://orcid.org/0000-0002-4634-0591

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• Kirk A. Easley,

  Roles Data curation, Formal analysis, Project administration, Writing – review & editing

  Affiliation Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America

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• Neeta Shenvi,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America

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• Manoj Khadka,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Emory Integrated Lipidomics Core, Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Eric A. Ortlund,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Emory Integrated Lipidomics Core, Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Russell R. Kempker,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Henry M. Blumberg,

  Roles Conceptualization, Funding acquisition, Investigation, Resources, Supervision, Writing – review & editing

  Affiliation Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America

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• Thomas R. Ziegler

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Division of Endocrinology, Metabolism and Lipids and Center for Clinical and Molecular Nutrition, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America, Section of Endocrinology, Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, United States of America

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