GPR108, an NF-κB activator suppressed by TIRAP, negatively regulates TLR-triggered immune responses

• Danfeng Dong ,

  Contributed equally to this work with: Danfeng Dong, Haisheng Zhou

  Roles Data curation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Current address: Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

  Affiliations Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

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• Haisheng Zhou ,

  Contributed equally to this work with: Danfeng Dong, Haisheng Zhou

  Roles Data curation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Current address: Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, China

  Affiliations Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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• Soon-Young Na,

  Roles Investigation, Methodology, Visualization

  Current address: National Creative Research Initiatives Center for Nuclear Receptor Signals and Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, Republic of Korea

  Affiliations Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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• Rasma Niedra,

  Roles Investigation, Visualization

  Affiliation Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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• Yibing Peng,

  Roles Supervision, Writing – review & editing

  Current address: Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

  Affiliation Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

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• Huajun Wang,

  Roles Formal analysis

  Affiliation Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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• Brian Seed,

  Roles Funding acquisition, Investigation, Methodology, Supervision, Validation, Writing – review & editing

  Affiliations Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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• Guo Ling Zhou

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: gzhou@ccib.mgh.harvard.edu

  Affiliations Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

  http://orcid.org/0000-0001-5460-8693

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