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Open Access
Peer-reviewed
Research Article
Rhinovirus infections change DNA methylation and mRNA expression in children with asthma
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Martin Pech ,
Contributed equally to this work with: Martin Pech, Markus Weckmann
Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Visualization, Writing – original draft
Affiliation University Medical Center Schleswig-Holstein, Department of Pediatric Pneumology & Allergology, Campus Lübeck, Airway Research Center North (ARCN), Member of the German Center of Lung Research (DZL), Lübeck, Germany
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Markus Weckmann ,
Contributed equally to this work with: Martin Pech, Markus Weckmann
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Writing – review & editing
Affiliation University Medical Center Schleswig-Holstein, Department of Pediatric Pneumology & Allergology, Campus Lübeck, Airway Research Center North (ARCN), Member of the German Center of Lung Research (DZL), Lübeck, Germany
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Inke R. König,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation University of Lübeck, Institute for Medical Biometry and Statistics, Airway Research Center North (ARCN), Member of the German Center of Lung Research (DZL), Lübeck, Germany
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Andre Franke,
Roles Resources, Writing – review & editing
Affiliation Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany
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Femke-Anouska Heinsen,
Roles Resources, Software
Affiliation Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany
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Brian Oliver,
Roles Resources, Writing – review & editing
Affiliation University of Technology Sydney, and Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia
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Isabell Ricklefs,
Roles Data curation, Resources
Affiliation University Medical Center Schleswig-Holstein, Department of Pediatric Pneumology & Allergology, Campus Lübeck, Airway Research Center North (ARCN), Member of the German Center of Lung Research (DZL), Lübeck, Germany
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Oliver Fuchs,
Roles Resources
Affiliations University Medical Center Schleswig-Holstein, Department of Pediatric Pneumology & Allergology, Campus Lübeck, Airway Research Center North (ARCN), Member of the German Center of Lung Research (DZL), Lübeck, Germany, Department of Pediatric Respiratory Medicine, Inselspital, University Children's Hospital of Bern, University of Bern, Bern, Switzerland
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Klaus Rabe,
Roles Funding acquisition, Writing – review & editing
Affiliation LungenClinic Grosshansdorf, Department of Pneumology, Großhansdorf, Germany, Airway Research Center North (ARCN), Member of the German Center of Lung Research (DZL), Grosshansdorf, Germany
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Gesine Hansen,
Roles Funding acquisition, Writing – review & editing
Affiliation Hannover Medical School, Department of Paediatric Pneumology, Allergology and Neonatology, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center of Lung Research (DZL), Hannover, Germany
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Erika v. Mutius,
Roles Funding acquisition, Writing – review & editing
Affiliation Ludwig-Maximilians-University Munich, Dr. von Hauner Children's Hospital, Comprehensive Pneumology Center München (CPC-M), Member of the German Center of Lung Research (DZL), Munich, Germany
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Matthias V. Kopp ,
Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: matthias.kopp@uksh.de
Affiliation University Medical Center Schleswig-Holstein, Department of Pediatric Pneumology & Allergology, Campus Lübeck, Airway Research Center North (ARCN), Member of the German Center of Lung Research (DZL), Lübeck, Germany
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the ALLIANCE-study group
¶Membership of the German Center of Lung Research (DZL) is described in detail in the Acknowledgments.
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Rhinovirus infections change DNA methylation and mRNA expression in children with asthma
- Martin Pech,
- Markus Weckmann,
- Inke R. König,
- Andre Franke,
- Femke-Anouska Heinsen,
- Brian Oliver,
- Isabell Ricklefs,
- Oliver Fuchs,
- Klaus Rabe,
- Gesine Hansen
- Published: November 28, 2018
- https://doi.org/10.1371/journal.pone.0205275