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The arginase inhibitor Nω−hydroxy−nor−arginine (nor−NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target
- King Pan Ng,
- Aditi Manjeri,
- Lin Ming Lee,
- Zhu En Chan,
- Chin Yee Tan,
- Qiancheng Darren Tan,
- A'Qilah Majeed,
- Kian Leong Lee,
- Charles Chuah,
- Toshio Suda
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- Published: October 11, 2018
- https://doi.org/10.1371/journal.pone.0205254