http://orcid.org/0000-0002-0147-123X
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The arginase inhibitor Nω−hydroxy−nor−arginine (nor−NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target
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King Pan Ng ,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: ngkingp@mail.sysu.edu.cn (NPN); sintiong.ong@duke-nus.edu.sg (STO)
Current address: School of Medical, Sun Yat-Sen University, China
Affiliation Cancer and Stem Cell Biology Signature Research Program, Duke−NUS Medical School, Singapore, Singapore
⨯ - Aditi Manjeri,
- Lin Ming Lee,
- Zhu En Chan,
- Chin Yee Tan,
- Qiancheng Darren Tan,
- A'Qilah Majeed,
- Kian Leong Lee,
- Charles Chuah,
- Toshio Suda,
- S. Tiong Ong
The arginase inhibitor Nω−hydroxy−nor−arginine (nor−NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target
- King Pan Ng,
- Aditi Manjeri,
- Lin Ming Lee,
- Zhu En Chan,
- Chin Yee Tan,
- Qiancheng Darren Tan,
- A'Qilah Majeed,
- Kian Leong Lee,
- Charles Chuah,
- Toshio Suda
x
- Published: October 11, 2018
- https://doi.org/10.1371/journal.pone.0205254