Temporal clustering analysis of endothelial cell gene expression following exposure to a conventional radiotherapy dose fraction using Gaussian process clustering

Markus Heinonen; Fabien Milliat; Mohamed Amine Benadjaoud; Agnès François; Valérie Buard; Georges Tarlet; Florence d’Alché-Buc; Olivier Guipaud

doi:10.1371/journal.pone.0204960

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Open Access

Peer-reviewed

Research Article

Temporal clustering analysis of endothelial cell gene expression following exposure to a conventional radiotherapy dose fraction using Gaussian process clustering

Markus Heinonen,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Information and Computer Science, Aalto University, Aalto, Finland
⨯
Fabien Milliat,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Writing – review & editing

Affiliation Institute for Radiological Protection and Nuclear Safety (IRSN), PSE-SANTE, SERAMED, LRMed, Fontenay-aux-Roses, France
⨯
Mohamed Amine Benadjaoud,

Roles Conceptualization, Formal analysis, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliation Institute for Radiological Protection and Nuclear Safety (IRSN), PSE-SANTE, SERAMED, Fontenay-aux-Roses, France
⨯
Agnès François,

Roles Conceptualization, Investigation, Writing – review & editing

Affiliation Institute for Radiological Protection and Nuclear Safety (IRSN), PSE-SANTE, SERAMED, LRMed, Fontenay-aux-Roses, France
⨯
Valérie Buard,

Roles Investigation

Affiliation Institute for Radiological Protection and Nuclear Safety (IRSN), PSE-SANTE, SERAMED, LRMed, Fontenay-aux-Roses, France
⨯
Georges Tarlet,

Roles Investigation

Affiliation Institute for Radiological Protection and Nuclear Safety (IRSN), PSE-SANTE, SERAMED, LRMed, Fontenay-aux-Roses, France

http://orcid.org/0000-0002-4756-5127

⨯
Florence d’Alché-Buc,

Roles Conceptualization, Formal analysis, Investigation, Supervision, Validation, Writing – review & editing

Affiliation LTCI, Télécom ParisTech, Université Paris-Saclay, Paris, France
⨯
Olivier Guipaud

Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: olivier.guipaud@irsn.fr

Affiliation Institute for Radiological Protection and Nuclear Safety (IRSN), PSE-SANTE, SERAMED, LRMed, Fontenay-aux-Roses, France

http://orcid.org/0000-0001-8165-2075

⨯

Temporal clustering analysis of endothelial cell gene expression following exposure to a conventional radiotherapy dose fraction using Gaussian process clustering

Markus Heinonen,
Fabien Milliat,
Mohamed Amine Benadjaoud,
Agnès François,
Valérie Buard,
Georges Tarlet,
Florence d’Alché-Buc,
Olivier Guipaud

Published: October 3, 2018
https://doi.org/10.1371/journal.pone.0204960

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Gene expression
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Endothelial cells
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Radiation therapy
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