Pharmacokinetics of intramuscular alfaxalone and its echocardiographic, cardiopulmonary and sedative effects in healthy dogs

• Inga-Catalina Cruz-Benedetti,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Current address: Department of Anaesthesiology and Perioperative Intensive-Care Medicine, Veterinärmedizinische Universität Wien, Vienna, Austria

  Affiliation Université de Lyon, VetAgro Sup, GREAT, Marcy l’Etoile, France

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• Isabelle Bublot,

  Roles Investigation, Writing – original draft, Writing – review & editing

  Current address: Clinique Vétérinaire des Cerisioz, Cardiology, Saint-Priest, France

  Affiliation Université de Lyon, VetAgro Sup, Unit of Cardiology, Marcy l’Etoile, France

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• Thibault Ribas,

  Roles Data curation, Writing – original draft, Writing – review & editing

  Affiliation Azurvet, Hippodrome, Cagnes sur mer, France

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• Isabelle Fourel,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Université de Lyon, VetAgro Sup, INRA, USC1233, RS2GP, Marcy l’Etoile, France

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• Claus Vogl,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Animal Husbandry and Genetics, Section for Molecular Biology, Vetmeduni, Vienna, Austria

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• Claire Dubois,

  Roles Investigation

  Affiliation Université de Lyon, VetAgro Sup, GREAT, Marcy l’Etoile, France

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• Mathilde Milani,

  Roles Investigation

  Current address: Clinique Vétérinaire Calvisson, Cardiology, Calvisson, France

  Affiliation Université de Lyon, VetAgro Sup, Unit of Cardiology, Marcy l’Etoile, France

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• Keila Kazue Ida,

  Roles Data curation, Investigation, Writing – original draft, Writing – review & editing

  Current address: Anesthesiology and Veterinary Reanimation, Department of Companion Animals and Horses Clinics, University of Liège, Liège, Belgium

  Affiliations Université de Lyon, VetAgro Sup, GREAT, Marcy l’Etoile, France, Laboratory of Medical Investigation 8, Anaesthesiology, Medical School, University of São Paulo, São Paulo, Brazil

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• Karine Portier

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – review & editing

  * E-mail: karine.portier@vetagro-sup.fr

  Affiliations Université de Lyon, VetAgro Sup, GREAT, Marcy l’Etoile, France, Univ Lyon, CarMeN Laboratory, INSERM, INRA, INSA Lyon, Université Claude Bernard Lyon 1, Bron, France

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