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Open Access
Peer-reviewed
Research Article
LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response
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Inna Serganova,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft
Affiliation Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America
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Ivan J. Cohen,
Roles Methodology, Validation
Affiliation Gerstner Sloan Kettering Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America
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Kiranmayi Vemuri,
Roles Data curation, Formal analysis, Investigation, Methodology, Visualization
Affiliation Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America
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Masahiro Shindo,
Roles Methodology, Visualization
Current address: Department of Neurosurgery, Nozaki Tokushukai Hospital, Tanigawa, Daito-city, Osaka, Japan
Affiliation Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America
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Masatomo Maeda,
Roles Methodology
Affiliation Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America
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Mayuresh Mane,
Roles Formal analysis, Validation
Affiliation Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America
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Ekaterina Moroz,
Roles Investigation, Methodology
Current address: SageMedic Corp, MBC biolabs, San Francisco, CA, United States of America
Affiliation Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America
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Raya Khanin,
Roles Data curation, Methodology
Affiliation Bioinformatics Core, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America
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Jaya Satagopan,
Roles Formal analysis, Resources, Validation
Affiliation Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America
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Jason A. Koutcher,
Roles Conceptualization, Funding acquisition, Project administration
Affiliations Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America, Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America
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Ronald Blasberg
Roles Conceptualization, Data curation, Funding acquisition, Supervision, Writing – review & editing
* E-mail: blasberg@neuro1.mskcc.org
Affiliations Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America, Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America
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LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response
- Inna Serganova,
- Ivan J. Cohen,
- Kiranmayi Vemuri,
- Masahiro Shindo,
- Masatomo Maeda,
- Mayuresh Mane,
- Ekaterina Moroz,
- Raya Khanin,
- Jaya Satagopan,
- Jason A. Koutcher
- Published: September 24, 2018
- https://doi.org/10.1371/journal.pone.0203965