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Open Access
Peer-reviewed
Research Article
Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort
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Rosalia Emma,
Roles Conceptualization, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Clinical and Experimental Medicine – University of Catania, Catania, Italy
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Aruna T. Bansal,
Roles Formal analysis, Visualization, Writing – review & editing
Affiliation Acclarogen Ltd, St John’s Innovation Centre, Cambridge, United Kingdom
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Johan Kolmert,
Roles Data curation, Validation, Visualization, Writing – review & editing
Affiliations Division of Physiological Chemistry 2, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden, Centre for Allergy Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
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Craig E. Wheelock,
Roles Writing – review & editing
Affiliation Division of Physiological Chemistry 2, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
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Swen-Erik Dahlen,
Roles Writing – review & editing
Affiliation Centre for Allergy Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
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Matthew J. Loza,
Roles Data curation, Writing – review & editing
Affiliation Janssen Research & Development, LLC, Springhouse, Pennsylvania, United States of America
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Bertrand De Meulder,
Roles Writing – review & editing
Affiliation European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM, CIRI-UMR5308, Lyon, France
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Diane Lefaudeux,
Roles Writing – review & editing
Affiliation European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM, CIRI-UMR5308, Lyon, France
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Charles Auffray,
Roles Funding acquisition, Project administration, Writing – review & editing
Affiliation European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM, CIRI-UMR5308, Lyon, France
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Barbro Dahlen,
Roles Writing – review & editing
Affiliation Karolinska University Hospital & Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden
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Per S. Bakke,
Roles Writing – review & editing
Affiliation Department of Clinical Science, University of Bergen, Bergen, Norway
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Pascal Chanez,
Roles Writing – review & editing
Affiliation Département des Maladies Respiratoires, CIC Nord, INSERM U1067 Aix Marseille Université Marseille, Marseille, France
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Stephen J. Fowler,
Roles Investigation, Writing – review & editing
Affiliation Centre for Respiratory Medicine and Allergy, The University of Manchester, Manchester Academic Health Science Centre, University Hospital of South Manchester NHS Foundation Trust, Clinic, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, United Kingdom
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Ildiko Horvath,
Roles Writing – review & editing
Affiliation Department of Pulmonology, Semmelweis University, Budapest, Hungary
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Paolo Montuschi,
Roles Writing – review & editing
Affiliation Faculty of Medicine, Catholic University of the Sacred Heart, Rome, Italy
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Norbert Krug,
Roles Writing – review & editing
Affiliation Fraunhofer Institute for Toxicology and Experimental Medicine Hannover, Germany
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Marek Sanak,
Roles Writing – review & editing
Affiliation Department of Medicine, Jagiellonian University Medical School, Krakow, Poland
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Thomas Sandstrom,
Roles Writing – review & editing
Affiliation Dept of Public Health and Clinical Medicine, Medicine, Umeå University, Umeå, Sweden
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Dominick E. Shaw,
Roles Investigation, Writing – review & editing
Affiliation Respiratory Research Unit, University of Nottingham, Nottingham, United Kingdom
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Louise J. Fleming,
Roles Investigation, Writing – review & editing
Affiliation National Heart & Lung Institute, Imperial College, London, United Kingdom
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Ratko Djukanovic,
Roles Funding acquisition, Project administration, Writing – review & editing
Affiliation NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton, United Kingdom
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Peter H. Howarth,
Roles Writing – review & editing
Affiliation NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton, United Kingdom
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Florian Singer,
Roles Writing – review & editing
Affiliations University Children’s Hospital Bern, Bern, Switzerland, University Children’s Hospital Zurich, Zurich, Switzerland
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Ana R. Sousa,
Roles Writing – review & editing
Affiliation Respiratory Therapy Unit, GlaxoSmithKline, London, United Kingdom
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Peter J. Sterk,
Roles Funding acquisition, Project administration, Writing – review & editing
Affiliation Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
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Julie Corfield,
Roles Writing – review & editing
Affiliations AstraZeneca R&D, Mölndal, Sweden, Areteva R&D, Nottingham, United Kingdom
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Ioannis Pandis,
Roles Writing – review & editing
Affiliation Data Science Institute, South Kensington Campus, Imperial College London, London, United Kingdom
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Kian F. Chung,
Roles Funding acquisition, Project administration, Writing – review & editing
Affiliation National Heart & Lung Institute, Imperial College, London, United Kingdom
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Ian M. Adcock,
Roles Funding acquisition, Project administration, Writing – review & editing
Affiliation National Heart & Lung Institute, Imperial College, London, United Kingdom
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René Lutter,
Roles Writing – review & editing
Affiliation Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
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Lorena Fabbella,
Roles Writing – review & editing
Affiliation Department of Clinical and Experimental Medicine – University of Catania, Catania, Italy
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Massimo Caruso ,
Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing
* E-mail: mascaru@unict.it
Affiliations Department of Clinical and Experimental Medicine – University of Catania, Catania, Italy, Department of Biomedical and Biotechnological Sciences (BIOMETEC), University of Catania, Catania, Italy
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U-BIOPRED Study Group
¶Membership of the U-BIOPRED study group is provided in
⨯S5 Table . - [ view all ]
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Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort
- Rosalia Emma,
- Aruna T. Bansal,
- Johan Kolmert,
- Craig E. Wheelock,
- Swen-Erik Dahlen,
- Matthew J. Loza,
- Bertrand De Meulder,
- Diane Lefaudeux,
- Charles Auffray,
- Barbro Dahlen
- Published: September 21, 2018
- https://doi.org/10.1371/journal.pone.0203874