Routine data underestimates the incidence of first-line antiretroviral drug discontinuations due to adverse drug reactions: Observational study in two South African cohorts

• Reneé de Waal,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa

  http://orcid.org/0000-0001-6171-2181

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• Karen Cohen,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Writing – review & editing

  Affiliation Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa

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• Andrew Boulle,

  Roles Conceptualization, Data curation, Methodology, Writing – review & editing

  Affiliation Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa

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• Matthew P. Fox,

  Roles Data curation, Writing – review & editing

  Affiliations Boston University Departments of Epidemiology and Global Health, Boston, MA, United States of America, Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa

  http://orcid.org/0000-0001-9887-0634

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• Gary Maartens,

  Roles Conceptualization, Writing – review & editing

  Affiliation Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa

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• Ehimario U. Igumbor,

  Roles Funding acquisition, Writing – review & editing

  Affiliation US Centers for Disease Control and Prevention, Division of Global HIV & TB, Pretoria, South Africa

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• Mary-Ann Davies

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing

  * E-mail: mary-ann.davies@uct.ac.za

  Affiliation Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa

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