Substantial improvement of toyocamycin production in Streptomyces diastatochromogenes by cumulative drug-resistance mutations

• Xu-Ping Shentu ,

  Contributed equally to this work with: Xu-Ping Shentu, Zhen-Yan Cao

  Roles Writing – original draft

  Affiliation Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, College of Life Sciences, China Jiliang University, Hangzhou, China

  http://orcid.org/0000-0003-4524-0334

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• Zhen-Yan Cao ,

  Contributed equally to this work with: Xu-Ping Shentu, Zhen-Yan Cao

  Roles Formal analysis

  Affiliation Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, College of Life Sciences, China Jiliang University, Hangzhou, China

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• Yin Xiao,

  Roles Data curation

  Affiliation Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, College of Life Sciences, China Jiliang University, Hangzhou, China

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• Gu Tang,

  Roles Data curation

  Affiliation Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, College of Life Sciences, China Jiliang University, Hangzhou, China

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• Kozo Ochi,

  Roles Writing – review & editing

  Affiliation Department of Life Science, Hiroshima Institute of Technology, Hiroshima, Japan

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• Xiao-Ping Yu

  Roles Supervision

  * E-mail: yxp@cjlu.edu.cn

  Affiliation Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, College of Life Sciences, China Jiliang University, Hangzhou, China

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