Novel isothiacalothrixin B analogues exhibit cytotoxic activity on human colon cancer cells in vitro by inducing irreversible DNA damage

• Nachiappan Dhatchana Moorthy,

  Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft

  Affiliations Department of Biochemistry, University of Madras, Guindy Campus, Chennai, India, Department of Biotechnology, Orchid Pharma Limited, Chennai, India

  http://orcid.org/0000-0002-0071-4762

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• Bose Muthu Ramalingam,

  Roles Conceptualization, Investigation, Methodology

  Affiliation Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai, India

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• Saleem Iqbal,

  Roles Investigation, Methodology, Software, Validation, Visualization

  Affiliation Center for Advanced studies in Crystallography & Biophysics, University of Madras, Chennai, India

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• Arasambattu K Mohanakrishnan,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai, India

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• Krishnasamy Gunasekaran,

  Roles Investigation, Methodology, Supervision

  Affiliation Center for Advanced studies in Crystallography & Biophysics, University of Madras, Chennai, India

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• Elangovan Vellaichamy

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: vellaie@unom.ac.in, vellaie@gmail.com

  Affiliation Department of Biochemistry, University of Madras, Guindy Campus, Chennai, India

  http://orcid.org/0000-0003-4151-4828

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