Characterization of new, efficient Mycobacterium tuberculosis topoisomerase-I inhibitors and their interaction with human ABC multidrug transporters

• Csilla Temesszentandrási-Ambrus,

  Roles Investigation, Writing – original draft

  Affiliations Institute of Enzymology, RCNS-HAS, Budapest, Hungary, Molecular Medicine Doctoral School, Semmelweis University, Budapest, Hungary

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• Szilárd Tóth,

  Roles Investigation, Methodology

  Affiliation Institute of Enzymology, RCNS-HAS, Budapest, Hungary

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• Rinkee Verma,

  Roles Data curation, Investigation

  Affiliation Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India

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• Péter Bánhegyi,

  Roles Investigation, Writing – original draft

  Affiliation Vichem Chemie Research Ltd., Budapest, Hungary

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• István Szabadkai,

  Roles Investigation

  Affiliation Vichem Chemie Research Ltd., Budapest, Hungary

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• Ferenc Baska,

  Roles Investigation

  Affiliation Vichem Chemie Research Ltd., Budapest, Hungary

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• Csaba Szántai-Kis,

  Roles Data curation

  Affiliation Vichem Chemie Research Ltd., Budapest, Hungary

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• Ruben C. Hartkoorn,

  Roles Conceptualization, Investigation, Writing – original draft

  Affiliation Chemical Biology of Antibiotics, Center for Infection and Immunity, Inserm, CNRS, Institut Pasteur de Lille, Université de Lille, Lille, France

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• Mary A. Lingerfelt,

  Roles Data curation, Visualization, Writing – original draft

  Affiliation Collaborations Pharmaceuticals, Inc., Raleigh, United States of America

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• Balázs Sarkadi,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation Institute of Enzymology, RCNS-HAS, Budapest, Hungary

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• Gergely Szakács,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation Institute of Enzymology, RCNS-HAS, Budapest, Hungary

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• László Őrfi,

  Roles Conceptualization

  Affiliations Vichem Chemie Research Ltd., Budapest, Hungary, Department of Pharmaceutical Chemistry, Semmelweis University, Budapest, Hungary

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• Valakunja Nagaraja,

  Roles Conceptualization, Funding acquisition, Supervision

  Affiliation Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India

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• Sean Ekins,

  Roles Conceptualization, Software, Supervision

  Affiliation Collaborations Pharmaceuticals, Inc., Raleigh, United States of America

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• Ágnes Telbisz

  Roles Investigation, Supervision, Writing – original draft

  * E-mail: telbisz.agnes@ttk.mta.hu

  Affiliation Institute of Enzymology, RCNS-HAS, Budapest, Hungary

  http://orcid.org/0000-0003-0972-4606

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