Efavirenz reduces renal excretion of lamivudine in rats by inhibiting organic cation transporters (OCT, Oct) and multidrug and toxin extrusion proteins (MATE, Mate)

• Martina Ceckova ,

  Contributed equally to this work with: Martina Ceckova, Josef Reznicek

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Pharmacology and Toxicology, Charles University in Prague, Faculty of Pharmacy in Hradec Kralove, Hradec Kralove, Czech Republic

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• Josef Reznicek ,

  Contributed equally to this work with: Martina Ceckova, Josef Reznicek

  Roles Investigation, Methodology, Writing – original draft

  Affiliation Department of Pharmacology and Toxicology, Charles University in Prague, Faculty of Pharmacy in Hradec Kralove, Hradec Kralove, Czech Republic

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• Birgit Deutsch,

  Roles Investigation, Methodology, Writing – original draft

  Affiliation Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

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• Martin F. Fromm,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

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• Frantisek Staud

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: frantisek.staud@faf.cuni.cz

  Affiliation Department of Pharmacology and Toxicology, Charles University in Prague, Faculty of Pharmacy in Hradec Kralove, Hradec Kralove, Czech Republic

  http://orcid.org/0000-0001-6712-097X

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