Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies

• Tracy Murray-Stewart,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

  http://orcid.org/0000-0001-8679-6414

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• Matthew Dunworth,

  Roles Data curation, Formal analysis, Investigation, Resources

  Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Yuan Lui,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Francis M. Giardiello,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliations Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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• Patrick M. Woster,

  Roles Funding acquisition, Resources, Visualization, Writing – review & editing

  Affiliation Department of Drug Discovery and Biomedical Sciences, College of Pharmacy, Medical University of South Carolina, Charleston, SC, United States of America

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• Robert A. Casero Jr

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: rcasero@jhmi.edu

  Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America

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