Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils

Anne-Sophie Archambault; Caroline Turcotte; Cyril Martin; Véronique Provost; Marie-Chantal Larose; Catherine Laprise; Jamila Chakir; Élyse Bissonnette; Michel Laviolette; Ynuk Bossé; Nicolas Flamand

doi:10.1371/journal.pone.0202424

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Peer-reviewed

Research Article

Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils

Anne-Sophie Archambault ,

Contributed equally to this work with: Anne-Sophie Archambault, Caroline Turcotte

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliation Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Département de médecine, Faculté de médecine, Université Laval, Québec City, QC, Canada
⨯
Caroline Turcotte ,

Contributed equally to this work with: Anne-Sophie Archambault, Caroline Turcotte

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliation Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Département de médecine, Faculté de médecine, Université Laval, Québec City, QC, Canada
⨯
Cyril Martin,

Roles Conceptualization, Data curation, Formal analysis, Writing – review & editing

Affiliation Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Département de médecine, Faculté de médecine, Université Laval, Québec City, QC, Canada
⨯
Véronique Provost,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliation Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Département de médecine, Faculté de médecine, Université Laval, Québec City, QC, Canada
⨯
Marie-Chantal Larose,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Writing – review & editing

Affiliation Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Département de médecine, Faculté de médecine, Université Laval, Québec City, QC, Canada
⨯
Catherine Laprise,

Roles Conceptualization, Investigation, Writing – review & editing

Affiliation Centre intégré universitaire de santé et services sociaux du Saguenay–Lac-Saint-Jean, Département de sciences fondamentales, Université du Québec à Chicoutimi, Saguenay, QC, Canada
⨯
Jamila Chakir,

Roles Conceptualization, Investigation, Writing – review & editing

Affiliation Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Département de médecine, Faculté de médecine, Université Laval, Québec City, QC, Canada
⨯
Élyse Bissonnette,

Roles Conceptualization, Funding acquisition, Investigation, Writing – review & editing

Affiliation Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Département de médecine, Faculté de médecine, Université Laval, Québec City, QC, Canada
⨯
Michel Laviolette,

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – review & editing

Affiliation Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Département de médecine, Faculté de médecine, Université Laval, Québec City, QC, Canada
⨯
Ynuk Bossé,

Roles Conceptualization, Investigation, Writing – review & editing

Affiliation Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Département de médecine, Faculté de médecine, Université Laval, Québec City, QC, Canada
⨯
Nicolas Flamand

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: Nicolas.Flamand@criucpq.ulaval.ca

Affiliation Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec, Département de médecine, Faculté de médecine, Université Laval, Québec City, QC, Canada

http://orcid.org/0000-0001-5944-7200

⨯

Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils

Anne-Sophie Archambault,
Caroline Turcotte,
Cyril Martin,
Véronique Provost,
Marie-Chantal Larose,
Catherine Laprise,
Jamila Chakir,
Élyse Bissonnette,
Michel Laviolette,
Ynuk Bossé

Published: August 17, 2018
https://doi.org/10.1371/journal.pone.0202424

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