Studying additive interaction in a healthcare database: Case study of NSAIDs, cardiovascular profiles, and acute myocardial infarction

• Michèle Bally ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: michele.bally.chum@ssss.gouv.qc.ca

  Affiliation Department of Pharmacy and Research Center, University of Montreal Hospital, Montreal, Canada

  http://orcid.org/0000-0001-9587-7929

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• Lyne Nadeau,

  Roles Data curation, Software

  Affiliation Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, Canada

  http://orcid.org/0000-0003-0466-0260

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• James M. Brophy

  Roles Conceptualization, Resources, Supervision, Validation, Writing – review & editing

  Affiliations Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, Canada, Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Canada, Department of Medicine, McGill University Health Centre, Montreal, Canada

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