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Open Access
Peer-reviewed
Research Article
Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation
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R. Alessia Battista ,
Contributed equally to this work with: R. Alessia Battista, Massimo Resnati
Roles Conceptualization, Data curation, Formal analysis, Methodology
Affiliations Age Related Diseases Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy, Università Vita-Salute San Raffaele, Milano, Italy, Department of Otorhinolaryngology, San Raffaele Scientific Institute, Milano, Italy
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Massimo Resnati ,
Contributed equally to this work with: R. Alessia Battista, Massimo Resnati
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliation Age Related Diseases Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy
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Cecilia Facchi,
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliations Age Related Diseases Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy, Università Vita-Salute San Raffaele, Milano, Italy
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Elena Ruggieri,
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliations Age Related Diseases Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy, Università Vita-Salute San Raffaele, Milano, Italy
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Floriana Cremasco,
Roles Methodology
Affiliations Age Related Diseases Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy, Università Vita-Salute San Raffaele, Milano, Italy
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Francesca Paradiso,
Roles Methodology
Affiliations Age Related Diseases Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy, Università Vita-Salute San Raffaele, Milano, Italy
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Ugo Orfanelli,
Roles Methodology
Affiliation Age Related Diseases Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy
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Leone Giordano,
Roles Conceptualization
Affiliation Department of Otorhinolaryngology, San Raffaele Scientific Institute, Milano, Italy
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Mario Bussi,
Roles Conceptualization, Supervision
Affiliations Università Vita-Salute San Raffaele, Milano, Italy, Department of Otorhinolaryngology, San Raffaele Scientific Institute, Milano, Italy
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Simone Cenci ,
Roles Conceptualization, Data curation, Funding acquisition, Resources, Supervision, Writing – original draft
* E-mail: cenci.simone@hsr.it (S.C.); milan.enrico@hsr.it (E.M.)
¶‡ These authors also contributed equally to this work.
Affiliations Age Related Diseases Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy, Università Vita-Salute San Raffaele, Milano, Italy
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Enrico Milan
Roles Conceptualization, Funding acquisition, Investigation, Resources, Supervision, Validation, Writing – original draft
* E-mail: cenci.simone@hsr.it (S.C.); milan.enrico@hsr.it (E.M.)
¶‡ These authors also contributed equally to this work.
Affiliations Age Related Diseases Unit, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy, Università Vita-Salute San Raffaele, Milano, Italy
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Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation
- R. Alessia Battista,
- Massimo Resnati,
- Cecilia Facchi,
- Elena Ruggieri,
- Floriana Cremasco,
- Francesca Paradiso,
- Ugo Orfanelli,
- Leone Giordano,
- Mario Bussi,
- Simone Cenci
- Published: August 1, 2018
- https://doi.org/10.1371/journal.pone.0201621