Noninvasive vagus nerve stimulation alters neural response and physiological autonomic tone to noxious thermal challenge

• Imanuel Lerman ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: ilerman@ucsd.edu

  Current address: VA San Diego, La Jolla Village Dr, San Diego, CA (MC116A), United States of America

  Affiliations VA Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, CA, United States of America, Department of Anesthesiology, Center for Pain Medicine, University of California San Diego School of Medicine, La Jolla, CA, United States of America, Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA, United States of America

  http://orcid.org/0000-0002-6564-7222

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• Bryan Davis,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration

  Affiliation Department of Anesthesiology, Center for Pain Medicine, University of California San Diego School of Medicine, La Jolla, CA, United States of America

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• Mingxiong Huang,

  Roles Data curation, Writing – review & editing

  Affiliations Department of Radiology, University of California San Diego School of Medicine, La Jolla, CA, United States of America, Department of Radiology, VA San Diego Healthcare System, La Jolla, CA, United States of America

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• Charles Huang,

  Roles Methodology, Writing – review & editing

  Affiliations Department of Radiology, University of California San Diego School of Medicine, La Jolla, CA, United States of America, Department of Radiology, VA San Diego Healthcare System, La Jolla, CA, United States of America

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• Linda Sorkin,

  Roles Writing – original draft, Writing – review & editing

  Affiliation Department of Anesthesiology, Center for Pain Medicine, University of California San Diego School of Medicine, La Jolla, CA, United States of America

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• James Proudfoot,

  Roles Data curation, Formal analysis, Software, Validation, Visualization, Writing – review & editing

  Affiliation Department of Anesthesiology, Center for Pain Medicine, University of California San Diego School of Medicine, La Jolla, CA, United States of America

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• Edward Zhong,

  Roles Data curation, Software

  Affiliation Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA, United States of America

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• Donald Kimball,

  Roles Writing – review & editing

  Affiliation Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA, United States of America

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• Ramesh Rao,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA, United States of America

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• Bruce Simon,

  Roles Writing – review & editing

  Affiliation electroCore LLC, Basking Ridge NJ, United States of America

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• Andrea Spadoni,

  Roles Writing – review & editing

  Affiliations VA Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, CA, United States of America, Department of Psychiatry University of California San Diego School of Medicine, La Jolla, CA, United States of America

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• Irina Strigo,

  Roles Writing – review & editing

  Affiliation Department of Psychiatry, VA San Francisco Healthcare System, San Francisco, CA, United States of America

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• Dewleen G. Baker,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  Affiliations VA Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, CA, United States of America, Department of Psychiatry University of California San Diego School of Medicine, La Jolla, CA, United States of America

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• Alan N. Simmons

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations VA Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, CA, United States of America, Department of Psychiatry University of California San Diego School of Medicine, La Jolla, CA, United States of America

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