The spinal NR2BR/ERK2 pathway as a target for the central sensitization of collagen-induced arthritis pain

Yingming Xu; Kui Zhang; Jinlin Miao; Peng Zhao; Minghua Lv; Jia Li; Xianghui Fu; Xing Luo; Ping Zhu

doi:10.1371/journal.pone.0201021

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Open Access

Peer-reviewed

Research Article

The spinal NR2BR/ERK2 pathway as a target for the central sensitization of collagen-induced arthritis pain

Yingming Xu ,

Contributed equally to this work with: Yingming Xu, Kui Zhang

Roles Conceptualization, Data curation, Investigation, Writing – original draft

Affiliation Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Kui Zhang ,

Contributed equally to this work with: Yingming Xu, Kui Zhang

Roles Conceptualization, Investigation, Project administration, Writing – review & editing

Affiliation Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Jinlin Miao,

Roles Data curation, Investigation

Affiliation Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Peng Zhao,

Roles Data curation, Investigation

Affiliations Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, China, Department of Hematology and Rheumatology, Hanzhong 3201 Hospital, Hanzhong, China
⨯
Minghua Lv,

Roles Formal analysis, Investigation

Affiliation Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Jia Li,

Roles Formal analysis, Methodology

Affiliation Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Xianghui Fu,

Roles Data curation, Investigation

Affiliation Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Xing Luo,

Roles Formal analysis

Affiliation Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Ping Zhu

Roles Conceptualization, Writing – review & editing

* E-mail: zhuping@fmmu.edu.cn

Affiliation Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, China

http://orcid.org/0000-0002-8391-4945

⨯

The spinal NR2BR/ERK2 pathway as a target for the central sensitization of collagen-induced arthritis pain

Yingming Xu,
Kui Zhang,
Jinlin Miao,
Peng Zhao,
Minghua Lv,
Jia Li,
Xianghui Fu,
Xing Luo,
Ping Zhu

Published: July 19, 2018
https://doi.org/10.1371/journal.pone.0201021

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