Optimization of multiplex quantitative polymerase chain reaction based on response surface methodology and an artificial neural network-genetic algorithm approach

• Ping Pan,

  Roles Data curation, Methodology, Validation, Writing – original draft

  Affiliation Hangzhou First People’s Hospital, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

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• Weifeng Jin,

  Roles Formal analysis, Software

  Affiliation College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

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• Xiaohong Li,

  Roles Formal analysis

  Affiliation College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

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• Yi Chen,

  Roles Data curation

  Affiliations Hangzhou First People’s Hospital, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China, Zhejiang Hospital, Hangzhou, Zhejiang, China

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• Jiahui Jiang,

  Roles Data curation

  Affiliation Hangzhou First People’s Hospital, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

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• Haitong Wan,

  Roles Validation

  Affiliation College of Life Science, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

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• Daojun Yu

  Roles Project administration, Resources, Writing – review & editing

  * E-mail: yudaojun98@163.com

  Affiliations Hangzhou First People’s Hospital, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China, Department of Clinical Laboratory, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

  http://orcid.org/0000-0003-0855-7420

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