NorUDCA promotes degradation of α1-antitrypsin mutant Z protein by inducing autophagy through AMPK/ULK1 pathway

• Youcai Tang,

  Roles Conceptualization, Formal analysis, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Pediatrics and Biochemistry, Saint Louis University, and Cardinal Glennon Children’s Medical Center, St. Louis, Missouri, United States of America, Pediatrics and Science & Education, the Fifth Affiliated Hospital, Zhengzhou University, Zhengzhou, China

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• Keith S. Blomenkamp,

  Roles Data curation, Formal analysis, Methodology, Resources, Validation, Writing – review & editing

  Affiliation Pediatrics and Biochemistry, Saint Louis University, and Cardinal Glennon Children’s Medical Center, St. Louis, Missouri, United States of America

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• Peter Fickert,

  Roles Resources, Writing – review & editing

  Affiliation Research Unit for Experimental and Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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• Michael Trauner,

  Roles Resources, Writing – review & editing

  Affiliation Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

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• Jeffrey H. Teckman

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: teckmanj@slu.edu

  Affiliation Pediatrics and Biochemistry, Saint Louis University, and Cardinal Glennon Children’s Medical Center, St. Louis, Missouri, United States of America

  http://orcid.org/0000-0002-4870-2621

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