Flavonoid compound icariin enhances BMP-2 induced differentiation and signalling by targeting to connective tissue growth factor (CTGF) in SAMP6 osteoblasts

• Bing Xu ,

  Contributed equally to this work with: Bing Xu, Xueqiang Wang

  Roles Investigation, Methodology, Writing – original draft

  Affiliation Integrated Traditional Chinese and Western Medicine Hospital of Wenzhou Affilated Hospital of Zhejiang Chinese Medicine University, Zhe Jiang, China

  ⨯
• Xueqiang Wang ,

  Contributed equally to this work with: Bing Xu, Xueqiang Wang

  Roles Investigation, Methodology

  Affiliation Department of Sport Rehabilitation, Shanghai University of Sport, Shanghai, China

  ⨯
• Chengliang Wu,

  Roles Data curation, Investigation

  Affiliation Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

  ⨯
• Lihe Zhu,

  Roles Data curation, Software

  Affiliation Integrated Traditional Chinese and Western Medicine Hospital of Wenzhou Affilated Hospital of Zhejiang Chinese Medicine University, Zhe Jiang, China

  ⨯
• Ou Chen,

  Roles Data curation, Investigation

  Affiliation Integrated Traditional Chinese and Western Medicine Hospital of Wenzhou Affilated Hospital of Zhejiang Chinese Medicine University, Zhe Jiang, China

  ⨯
• Xiaofeng Wang

  Roles Funding acquisition, Investigation, Software, Writing – review & editing

  * E-mail: wzwxfs@139.com

  Affiliation Integrated Traditional Chinese and Western Medicine Hospital of Wenzhou Affilated Hospital of Zhejiang Chinese Medicine University, Zhe Jiang, China

  http://orcid.org/0000-0002-3927-1049

  ⨯