pH plays a role in the mode of action of trimethoprim on Escherichia coli

• Haitham AlRabiah,

  Roles Conceptualization, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliations School of Chemistry and Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom, Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

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• J. William Allwood,

  Roles Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliations School of Chemistry and Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom, Environmental and Biochemical Sciences Group, The James Hutton Institute, Invergowrie, Dundee, Scotland United Kingdom

  http://orcid.org/0000-0001-6433-2694

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• Elon Correa,

  Roles Data curation, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing

  Affiliation School of Chemistry and Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom

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• Yun Xu,

  Roles Data curation, Formal analysis, Software, Writing – original draft, Writing – review & editing

  Affiliation School of Chemistry and Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom

  http://orcid.org/0000-0003-3228-5111

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• Royston Goodacre

  Roles Conceptualization, Funding acquisition, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: roy.goodacre@manchester.ac.uk

  Affiliation School of Chemistry and Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom

  http://orcid.org/0000-0003-2230-645X

  ⨯