Sustained-release lidocaine sheet for pain following tooth extraction: A randomized, single-blind, dose-response, controlled, clinical study of efficacy and safety

Toshiyuki Suzuki; Kensuke Kosugi; Takashi Suto; Masaru Tobe; Yasuhiko Tabata; Satoshi Yokoo; Shigeru Saito

doi:10.1371/journal.pone.0200059

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Open Access

Peer-reviewed

Research Article

Sustained-release lidocaine sheet for pain following tooth extraction: A randomized, single-blind, dose-response, controlled, clinical study of efficacy and safety

Toshiyuki Suzuki ,

Contributed equally to this work with: Toshiyuki Suzuki, Kensuke Kosugi

Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources, Writing – original draft

* E-mail: toshis_free-hospital@yahoo.co.jp

Affiliation Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi-shi, Gunma, Japan

http://orcid.org/0000-0001-8216-2473

⨯
Kensuke Kosugi ,

Contributed equally to this work with: Toshiyuki Suzuki, Kensuke Kosugi

Roles Conceptualization, Data curation, Investigation, Methodology

Current address: Department of Anesthesiology, Division of General Medicine, Asahi University School of Dentistry, Mizuho-shi, Gifu, Japan

Affiliation Department of Oral and Maxillofacial Surgery, Gunma University Graduate School of Medicine, Maebashi-shi, Gunma, Japan
⨯
Takashi Suto,

Roles Supervision, Writing – review & editing

Affiliation Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi-shi, Gunma, Japan
⨯
Masaru Tobe,

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

Affiliation Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi-shi, Gunma, Japan
⨯
Yasuhiko Tabata,

Roles Resources, Supervision

Affiliation Department of Biomaterials, Field of Tissue Engineering, Institute for Frontier Medical Sciences, Kyoto University, Kyoto-shi, Kyoto, Japan
⨯
Satoshi Yokoo,

Roles Investigation, Methodology, Project administration, Supervision, Validation

Affiliation Department of Oral and Maxillofacial Surgery, Gunma University Graduate School of Medicine, Maebashi-shi, Gunma, Japan
⨯
Shigeru Saito

Roles Conceptualization, Methodology, Project administration, Supervision, Validation, Writing – review & editing

Affiliation Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi-shi, Gunma, Japan
⨯

Sustained-release lidocaine sheet for pain following tooth extraction: A randomized, single-blind, dose-response, controlled, clinical study of efficacy and safety

Toshiyuki Suzuki,
Kensuke Kosugi,
Takashi Suto,
Masaru Tobe,
Yasuhiko Tabata,
Satoshi Yokoo,
Shigeru Saito

Published: July 2, 2018
https://doi.org/10.1371/journal.pone.0200059

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Molars
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Dental and oral procedures
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