PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition

• Robert S. McNeill,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliation Pathobiology and Translational Science Graduate Program, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America

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• Emily E. Stroobant,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliation Department of Chemistry, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America

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• Erin Smithberger,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliation Pathobiology and Translational Science Graduate Program, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America

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• Demitra A. Canoutas,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliation Department of Biology, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America

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• Madison K. Butler,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliation Department of Biology, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America

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• Abigail K. Shelton,

  Roles Visualization, Writing – review & editing

  Affiliation Pathobiology and Translational Science Graduate Program, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America

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• Shrey D. Patel,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliation Department of Chemistry, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America

  http://orcid.org/0000-0001-5008-7616

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• Juanita C. Limas,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliation Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America

  http://orcid.org/0000-0001-6384-8787

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• Kasey R. Skinner,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliation Neurosciences Center, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America

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• Ryan E. Bash,

  Roles Investigation, Methodology

  Affiliation Departments of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America

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• Ralf S. Schmid,

  Roles Investigation, Methodology, Resources

  Affiliations Neurosciences Center, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America

  http://orcid.org/0000-0002-1721-5775

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• C. Ryan Miller

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rmiller@med.unc.edu

  Affiliations Pathobiology and Translational Science Graduate Program, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America, Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America, Neurosciences Center, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America, Departments of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America, Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC, United States of America

  http://orcid.org/0000-0002-0096-8762

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