Sema3a inhibits the differentiation of Raw264.7 cells to osteoclasts under 2Gy radiation by reducing inflammation

Bo Huang; Qin Zhang; Ying Yuan; Na Xin; Kun He; Yan Huang; Hua Tang; Ping Gong

doi:10.1371/journal.pone.0200000

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Open Access

Peer-reviewed

Research Article

Sema3a inhibits the differentiation of Raw264.7 cells to osteoclasts under 2Gy radiation by reducing inflammation

Bo Huang,

Roles Conceptualization, Data curation, Methodology, Project administration, Resources, Writing – original draft

Affiliations State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China, Dental Implant Center, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China
⨯
Qin Zhang,

Roles Investigation

Affiliations State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China, Dental Implant Center, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China
⨯
Ying Yuan,

Roles Data curation

Affiliations State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China, Dental Implant Center, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China
⨯
Na Xin,

Roles Data curation, Writing – original draft

Affiliations State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China, Dental Implant Center, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China
⨯
Kun He,

Roles Methodology, Software

Affiliation Dental Implant Center, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China
⨯
Yan Huang,

Roles Methodology, Project administration

Affiliations State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China, OMFS-IMPATH Research Group, Oral Imaging Center, Department of Imaging and Pathology, Biomedical Sciences Group, University of Leuven, Leuven, Belgium
⨯
Hua Tang ,

Roles Project administration

* E-mail: tanghua@126.com (HT); dentistgong@hotmail.com (PG)

Affiliation Dental Implant Center, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China
⨯
Ping Gong

Roles Project administration

* E-mail: tanghua@126.com (HT); dentistgong@hotmail.com (PG)

Affiliation Dental Implant Center, West China Hospital of Stomatology, Sichuan University, Chengdu, PR China

http://orcid.org/0000-0002-4782-1741

⨯

Sema3a inhibits the differentiation of Raw264.7 cells to osteoclasts under 2Gy radiation by reducing inflammation

Bo Huang,
Qin Zhang,
Ying Yuan,
Na Xin,
Kun He,
Yan Huang,
Hua Tang,
Ping Gong

Published: July 5, 2018
https://doi.org/10.1371/journal.pone.0200000

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Osteoclasts
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Apoptosis
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Bone resorption
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Radiation therapy
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Cell differentiation
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Inflammation
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Cell migration
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Gamma radiation
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