A classification modeling approach for determining metabolite signatures in osteoarthritis

• Jason S. Rockel ,

  Contributed equally to this work with: Jason S. Rockel, Weidong Zhang

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Arthritis Program, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada

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• Weidong Zhang ,

  Contributed equally to this work with: Jason S. Rockel, Weidong Zhang

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliations Discipline of Genetics, Faculty of Medicine, Memorial University of Newfoundland, St John’s, Newfoundland, Canada, School of Pharmaceutical Sciences, Jilin University, Changchun, P.R. China

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• Konstantin Shestopaloff,

  Roles Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Arthritis Program, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada

  ⨯
• Sergei Likhodii,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Laboratory Medicine, Faculty of Medicine, Memorial University of Newfoundland, St John’s, Newfoundland, Canada

  ⨯
• Guang Sun,

  Roles Data curation, Writing – review & editing

  Affiliation Discipline of Medicine, Faculty of Medicine, Memorial University of Newfoundland, St John’s, Newfoundland, Canada

  ⨯
• Andrew Furey,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Surgery, Faculty of Medicine, Memorial University of Newfoundland, St John’s, Newfoundland, Canada

  ⨯
• Edward Randell,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Laboratory Medicine, Faculty of Medicine, Memorial University of Newfoundland, St John’s, Newfoundland, Canada

  ⨯
• Kala Sundararajan,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliations Arthritis Program, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada

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• Rajiv Gandhi,

  Roles Conceptualization, Writing – review & editing

  Affiliations Arthritis Program, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada, Department of Surgery, University of Toronto, Toronto, Ontario, Canada

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• Guangju Zhai ,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: guangju.zhai@med.mun.ca (GZ); mohit.Kapoor@uhnresearch.ca (MK)

  ¶‡ These authors are equal senior authors on this work.

  Affiliations Discipline of Genetics, Faculty of Medicine, Memorial University of Newfoundland, St John’s, Newfoundland, Canada, Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia

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• Mohit Kapoor

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: guangju.zhai@med.mun.ca (GZ); mohit.Kapoor@uhnresearch.ca (MK)

  ¶‡ These authors are equal senior authors on this work.

  Affiliations Arthritis Program, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada, Department of Surgery, University of Toronto, Toronto, Ontario, Canada, Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada

  http://orcid.org/0000-0001-9877-0772

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