Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma

Ayguen Sahin; Carlos Sanchez; Szofia Bullain; Peter Waterman; Ralph Weissleder; Bob S. Carter

doi:10.1371/journal.pone.0199414

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Open Access

Peer-reviewed

Research Article

Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma

Ayguen Sahin ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

* E-mail: ayguensahin@gmail.com

Current address: Cancer Education and Research Institute, Cambridge, MA, United States of America

Affiliation HMS-MGH Center for Nervous System Repair, Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, United States of America

http://orcid.org/0000-0001-9247-8383

⨯
Carlos Sanchez,

Roles Investigation

Current address: University of New Mexico, NM, United States of America

Affiliation HMS-MGH Center for Nervous System Repair, Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, United States of America
⨯
Szofia Bullain,

Roles Resources

Current address: University of California-Irvine, Irvine, CA, United States of America

Affiliation HMS-MGH Center for Nervous System Repair, Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, United States of America
⨯
Peter Waterman,

Roles Formal analysis, Investigation

Current address: DNANexus, Mountainview, CA, United States of America

Affiliation Center for Systems Biology, Massachusetts General Hospital, Boston, MA, United States of America
⨯
Ralph Weissleder,

Roles Resources

Affiliation Center for Systems Biology, Massachusetts General Hospital, Boston, MA, United States of America
⨯
Bob S. Carter

Roles Funding acquisition, Writing – review & editing

Affiliation HMS-MGH Center for Nervous System Repair, Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, United States of America
⨯

Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma

Ayguen Sahin,
Carlos Sanchez,
Szofia Bullain,
Peter Waterman,
Ralph Weissleder,
Bob S. Carter

Published: July 5, 2018
https://doi.org/10.1371/journal.pone.0199414

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