Software-aided workflow for predicting protease-specific cleavage sites using physicochemical properties of the natural and unnatural amino acids in peptide-based drug discovery

• Tatiana Radchenko ,

  Contributed equally to this work with: Tatiana Radchenko, Ismael Zamora

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: tatiana.radchenko01@estudiant.upf.edu (TR); ismael.zamora@leadmolecular.com (IZ)

  Affiliations Pompeu Fabra University, Barcelona, Spain, Lead Molecular Design, S. L, Sant Cugat del Vallés, Spain

  http://orcid.org/0000-0003-4962-7229

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• Fabien Fontaine ,

  Roles Investigation, Software, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Lead Molecular Design, S. L, Sant Cugat del Vallés, Spain

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• Luca Morettoni ,

  Roles Methodology, Software, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Molecular Discovery Ltd, London, United Kingdom

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• Ismael Zamora

  Contributed equally to this work with: Tatiana Radchenko, Ismael Zamora

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – review & editing

  * E-mail: tatiana.radchenko01@estudiant.upf.edu (TR); ismael.zamora@leadmolecular.com (IZ)

  Affiliations Pompeu Fabra University, Barcelona, Spain, Lead Molecular Design, S. L, Sant Cugat del Vallés, Spain

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