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Open Access
Peer-reviewed
Research Article
Whole blood transcriptome analysis in amyotrophic lateral sclerosis: A biomarker study
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Wouter van Rheenen,
Roles Data curation, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
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Frank P. Diekstra,
Roles Data curation
Affiliation Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
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Oliver Harschnitz,
Roles Conceptualization, Writing – review & editing
Affiliations Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
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Henk-Jan Westeneng,
Roles Methodology
Affiliation Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
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Kristel R. van Eijk,
Roles Data curation
Affiliation Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
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Christiaan G. J. Saris,
Roles Data curation
Current address: Department of Neurology Nijmegen Neuromuscular Center, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands
Affiliation Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
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Ewout J. N. Groen,
Roles Data curation
Current address: Centre for Integrative Physiology and Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom
Affiliations Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
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Michael A. van Es,
Roles Data curation, Writing – review & editing
Affiliation Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
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Hylke M. Blauw,
Roles Data curation
Affiliation Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
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Paul W. J. van Vught,
Roles Data curation
Affiliation Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
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Jan H. Veldink ,
Contributed equally to this work with: Jan H. Veldink, Leonard H. van den Berg
Roles Funding acquisition, Methodology, Supervision, Writing – review & editing
Affiliation Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
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Leonard H. van den Berg
Contributed equally to this work with: Jan H. Veldink, Leonard H. van den Berg
Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing
* E-mail: L.H.vandenBerg@umcutrecht.nl
Affiliation Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands
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Whole blood transcriptome analysis in amyotrophic lateral sclerosis: A biomarker study
- Wouter van Rheenen,
- Frank P. Diekstra,
- Oliver Harschnitz,
- Henk-Jan Westeneng,
- Kristel R. van Eijk,
- Christiaan G. J. Saris,
- Ewout J. N. Groen,
- Michael A. van Es,
- Hylke M. Blauw,
- Paul W. J. van Vught
- Published: June 25, 2018
- https://doi.org/10.1371/journal.pone.0198874