Age-related endolysosome dysfunction in the rat urothelium

Steven T. Truschel; Dennis R. Clayton; Jonathan M. Beckel; Jonathan G. Yabes; Yi Yao; Amanda Wolf-Johnston; Lori A. Birder; Gerard Apodaca

doi:10.1371/journal.pone.0198817

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Open Access

Peer-reviewed

Research Article

Age-related endolysosome dysfunction in the rat urothelium

Steven T. Truschel,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America

http://orcid.org/0000-0003-3394-6006

⨯
Dennis R. Clayton,

Roles Data curation, Formal analysis

Affiliation Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America
⨯
Jonathan M. Beckel,

Roles Data curation, Formal analysis

Affiliation Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America

http://orcid.org/0000-0003-1390-2292

⨯
Jonathan G. Yabes,

Roles Formal analysis

Affiliations Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America, Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, United States of America
⨯
Yi Yao,

Roles Formal analysis

Affiliations Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America, Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, United States of America
⨯
Amanda Wolf-Johnston,

Roles Resources

Affiliation Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America
⨯
Lori A. Birder,

Roles Funding acquisition, Resources

Affiliations Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America, Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America
⨯
Gerard Apodaca

Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

* E-mail: gla6@pitt.edu

Affiliations Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America, Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America
⨯

Age-related endolysosome dysfunction in the rat urothelium

Steven T. Truschel,
Dennis R. Clayton,
Jonathan M. Beckel,
Jonathan G. Yabes,
Yi Yao,
Amanda Wolf-Johnston,
Lori A. Birder,
Gerard Apodaca

Published: June 8, 2018
https://doi.org/10.1371/journal.pone.0198817

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Lysosomes
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Bladder
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Cellular structures and organelles
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Urothelium
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Vesicles
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Age groups
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Cell membranes
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Aging
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