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Open Access
Peer-reviewed
Research Article
A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice
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Neha R. Deshpande ,
Contributed equally to this work with: Neha R. Deshpande, Jennifer L. Uhrlaub
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Department of Immunobiology, The University of Arizona College of Medicine, Tucson, AZ, United States of America, The BIO-5 Institute, The University of Arizona College of Medicine, Tucson, AZ, United States of America, The Arizona Center on Aging, The University of Arizona College of Medicine, Tucson, AZ, United States of America
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Jennifer L. Uhrlaub ,
Contributed equally to this work with: Neha R. Deshpande, Jennifer L. Uhrlaub
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliations Department of Immunobiology, The University of Arizona College of Medicine, Tucson, AZ, United States of America, The BIO-5 Institute, The University of Arizona College of Medicine, Tucson, AZ, United States of America, The Arizona Center on Aging, The University of Arizona College of Medicine, Tucson, AZ, United States of America
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Sing Sing Way,
Roles Resources, Writing – review & editing
Affiliation Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States of America
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Janko Nikolich-Žugich ,
Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing
* E-mail: mkuhns@email.arizona.edu (MSK); nikolich@email.arizona.edu (JNZ)
Affiliations Department of Immunobiology, The University of Arizona College of Medicine, Tucson, AZ, United States of America, The BIO-5 Institute, The University of Arizona College of Medicine, Tucson, AZ, United States of America, The Arizona Center on Aging, The University of Arizona College of Medicine, Tucson, AZ, United States of America
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Michael S. Kuhns
Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing
* E-mail: mkuhns@email.arizona.edu (MSK); nikolich@email.arizona.edu (JNZ)
Affiliations Department of Immunobiology, The University of Arizona College of Medicine, Tucson, AZ, United States of America, The BIO-5 Institute, The University of Arizona College of Medicine, Tucson, AZ, United States of America, The Arizona Center on Aging, The University of Arizona College of Medicine, Tucson, AZ, United States of America
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A disconnect between precursor frequency, expansion potential, and site-specific CD4+ T cell responses in aged mice
- Neha R. Deshpande,
- Jennifer L. Uhrlaub,
- Sing Sing Way,
- Janko Nikolich-Žugich,
- Michael S. Kuhns
- Published: June 4, 2018
- https://doi.org/10.1371/journal.pone.0198354