Renoprotective effects of dexmedetomidine against ischemia-reperfusion injury in streptozotocin-induced diabetic rats

Seung Hyun Kim; Ji Hae Jun; Ju Eun Oh; Eun-Jung Shin; Young Jun Oh; Yong Seon Choi

doi:10.1371/journal.pone.0198307

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Open Access

Peer-reviewed

Research Article

Renoprotective effects of dexmedetomidine against ischemia-reperfusion injury in streptozotocin-induced diabetic rats

Seung Hyun Kim,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Anesthesiology and Pain Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea

http://orcid.org/0000-0003-2127-6324

⨯
Ji Hae Jun,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Writing – original draft

Affiliation Anesthesia and Pain Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
⨯
Ju Eun Oh,

Roles Data curation, Formal analysis, Project administration, Resources, Software

Affiliation Anesthesia and Pain Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
⨯
Eun-Jung Shin,

Roles Data curation, Formal analysis, Project administration, Resources, Software

Affiliation Anesthesia and Pain Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
⨯
Young Jun Oh,

Roles Methodology, Supervision, Validation, Visualization, Writing – review & editing

Affiliations Department of Anesthesiology and Pain Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Anesthesia and Pain Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
⨯
Yong Seon Choi

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: yschoi@yuhs.ac

Affiliations Department of Anesthesiology and Pain Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Anesthesia and Pain Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea

http://orcid.org/0000-0002-5348-864X

⨯

Renoprotective effects of dexmedetomidine against ischemia-reperfusion injury in streptozotocin-induced diabetic rats

Seung Hyun Kim,
Ji Hae Jun,
Ju Eun Oh,
Eun-Jung Shin,
Young Jun Oh,
Yong Seon Choi

Published: August 16, 2018
https://doi.org/10.1371/journal.pone.0198307

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Diabetes mellitus
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Apoptosis
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Renal ischemia
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