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Open Access
Peer-reviewed
Research Article
Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes
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Charles B. Stauft,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliations Stony Brook University, Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, New York, United States of America, Codagenix, Incorporated, Farmingdale, New York, United States of America
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Sam H. Shen,
Roles Writing – original draft, Writing – review & editing
Affiliation Stony Brook University, Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, New York, United States of America
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Yutong Song,
Roles Writing – original draft, Writing – review & editing
Affiliation Stony Brook University, Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, New York, United States of America
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Oleksandr Gorbatsevych,
Roles Writing – original draft, Writing – review & editing
Affiliation Stony Brook University, Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, New York, United States of America
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Emmanuel Asare,
Roles Visualization, Writing – original draft, Writing – review & editing
Affiliation Stony Brook University, Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, New York, United States of America
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Bruce Futcher,
Roles Writing – original draft, Writing – review & editing
Affiliation Stony Brook University, Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, New York, United States of America
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Steffen Mueller,
Roles Writing – original draft, Writing – review & editing
Affiliations Stony Brook University, Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, New York, United States of America, Codagenix, Incorporated, Farmingdale, New York, United States of America
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Anne Payne,
Roles Writing – original draft, Writing – review & editing
Affiliation Wadsworth Center, New York State Department of Health, Slingerlands, New York, United States of America
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Matthew Brecher,
Roles Writing – original draft, Writing – review & editing
Affiliation Wadsworth Center, New York State Department of Health, Slingerlands, New York, United States of America
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Laura Kramer,
Roles Conceptualization, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing
Affiliations Wadsworth Center, New York State Department of Health, Slingerlands, New York, United States of America, School of Public Health, State University of New York at Albany, Rensselaer, New York, United States of America
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Eckard Wimmer
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: eckard.wimmer@stonybrook.edu
Affiliations Stony Brook University, Department of Molecular Genetics and Microbiology, Stony Brook University School of Medicine, Stony Brook, New York, United States of America, Codagenix, Incorporated, Farmingdale, New York, United States of America
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Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes
- Charles B. Stauft,
- Sam H. Shen,
- Yutong Song,
- Oleksandr Gorbatsevych,
- Emmanuel Asare,
- Bruce Futcher,
- Steffen Mueller,
- Anne Payne,
- Matthew Brecher,
- Laura Kramer
- Published: September 7, 2018
- https://doi.org/10.1371/journal.pone.0198303
- See the preprint