Four-dimensional, dynamic mosaicism is a hallmark of normal human skin that permits mapping of the organization and patterning of human epidermis during terminal differentiation

• Yun Wang ,

  Contributed equally to this work with: Yun Wang, Taro Masaki, Sikandar G. Khan

  Roles Data curation, Investigation, Validation, Writing – review & editing

  Affiliations Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States of America, Department of Dermatology, Peking University First Hospital, Beijing, China

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• Taro Masaki ,

  Contributed equally to this work with: Yun Wang, Taro Masaki, Sikandar G. Khan

  Roles Data curation, Investigation, Validation, Visualization, Writing – review & editing

  Affiliations Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States of America, Department of Dermatology, Kobe University School of Medicine, Kobe, Japan

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• Sikandar G. Khan ,

  Contributed equally to this work with: Yun Wang, Taro Masaki, Sikandar G. Khan

  Roles Data curation, Investigation, Validation, Writing – review & editing

  Affiliation Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States of America

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• Deborah Tamura,

  Roles Resources, Writing – review & editing

  Affiliation Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States of America

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• Christiane Kuschal,

  Roles Investigation, Writing – review & editing

  Affiliation Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States of America

  ⨯
• Megan Rogers,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States of America

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• John J. DiGiovanna ,

  Roles Conceptualization, Formal analysis, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ JJD and KHK are joint senior authors on this work.

  Affiliation Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States of America

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• Kenneth H. Kraemer

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: kraemerk@nih.gov

  ¶‡ JJD and KHK are joint senior authors on this work.

  Affiliation Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States of America

  http://orcid.org/0000-0002-2689-3316

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