Role of multimeric analysis of von Willebrand factor (VWF) in von Willebrand disease (VWD) diagnosis: Lessons from the PCM-EVW-ES Spanish project

• Almudena Pérez-Rodríguez ,

  Contributed equally to this work with: Almudena Pérez-Rodríguez, Javier Batlle, Irene Corrales, Nina Borràs, Francisco Vidal, María Fernanda López-Fernández

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Writing – original draft

  Affiliation Servicio Hematología, Complexo Hospitalario Universitario A Coruña, INIBIC, A Coruña, Spain

  ⨯
• Javier Batlle ,

  Contributed equally to this work with: Almudena Pérez-Rodríguez, Javier Batlle, Irene Corrales, Nina Borràs, Francisco Vidal, María Fernanda López-Fernández

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: francisco.javier.batlle.fonrodona@sergas.es

  Affiliation Servicio Hematología, Complexo Hospitalario Universitario A Coruña, INIBIC, A Coruña, Spain

  http://orcid.org/0000-0002-7931-2546

  ⨯
• Irene Corrales ,

  Contributed equally to this work with: Almudena Pérez-Rodríguez, Javier Batlle, Irene Corrales, Nina Borràs, Francisco Vidal, María Fernanda López-Fernández

  Roles Formal analysis, Resources, Supervision

  Affiliations Banc de Sang i Teixits, Barcelona, Spain, Unitat d’Hemofilia, Vall d’Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), Barcelona, Spain

  ⨯
• Nina Borràs ,

  Contributed equally to this work with: Almudena Pérez-Rodríguez, Javier Batlle, Irene Corrales, Nina Borràs, Francisco Vidal, María Fernanda López-Fernández

  Roles Formal analysis, Resources, Supervision

  Affiliations Banc de Sang i Teixits, Barcelona, Spain, Unitat d’Hemofilia, Vall d’Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), Barcelona, Spain

  ⨯
• Ángela Rodríguez-Trillo ,

  Roles Formal analysis, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Complexo Hospitalario Universitario A Coruña, INIBIC, A Coruña, Spain

  ⨯
• Esther Lourés ,

  Roles Formal analysis, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Complexo Hospitalario Universitario A Coruña, INIBIC, A Coruña, Spain

  ⨯
• Ana Rosa Cid ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario y Politécnico La Fe, Valencia, Spain

  ⨯
• Santiago Bonanad ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario y Politécnico La Fe, Valencia, Spain

  http://orcid.org/0000-0002-8390-8211

  ⨯
• Noelia Cabrera ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario y Politécnico La Fe, Valencia, Spain

  ⨯
• Andrés Moret ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario y Politécnico La Fe, Valencia, Spain

  ⨯
• Rafael Parra ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliations Unitat d’Hemofilia, Vall d’Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), Barcelona, Spain, Servicio Hematología, Hospital Universitari Vall d’Hebron, Barcelona, Spain

  ⨯
• María Eva Mingot-Castellano ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Regional Universitario de Málaga, Málaga, Spain

  http://orcid.org/0000-0001-9083-855X

  ⨯
• Nira Navarro ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario Dr. Negrín, Las Palmas de Gran Canaria, Spain

  ⨯
• Carmen Altisent ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitari Vall d’Hebron, Barcelona, Spain

  ⨯
• Rocío Pérez-Montes ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario Marqués de Valdecilla, Santander, Spain

  ⨯
• Shally Marcellini ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Salud Castilla y León, Segovia, Spain

  ⨯
• Ana Moreto ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario Cruces, Barakaldo, Spain

  ⨯
• Sonia Herrero ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario de Guadalajara, Guadalajara, Spain

  ⨯
• Inmaculada Soto ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario Central de Asturias, Oviedo, Spain

  ⨯
• Nuria Fernández Mosteirín ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario Miguel Servet, Zaragoza, Spain

  ⨯
• Víctor Jiménez-Yuste ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario La Paz, Madrid, Spain

  ⨯
• Nieves Alonso ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Infanta Cristina, Badajoz, Spain

  ⨯
• Aurora de Andrés Jacob ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Complexo Hospitalario Universitario Santiago de Compostela, Spain

  ⨯
• Emilia Fontanes ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario Lucus Augusti, Lugo, Spain

  ⨯
• Rosa Campos ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Jerez de la Frontera, Cádiz, Spain

  ⨯
• María José Paloma ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Virgen del Camino, Pamplona, Spain

  ⨯
• Nuria Bermejo ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital San Pedro de Alcántara, Cáceres, Spain

  ⨯
• Rubén Berrueco ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Sant Joan de Deu, Barcelona, Spain

  ⨯
• José Mateo ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Sta Creu i St Pau, Barcelona, Spain

  ⨯
• Karmele Arribalzaga ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario Fundación Alcorcón, Madrid, Spain

  ⨯
• Pascual Marco ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital General de Alicante, Alicante, Spain

  ⨯
• Ángeles Palomo ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Regional Universitario de Málaga, Málaga, Spain

  ⨯
• Nerea Castro Quismondo ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario 12 de Octubre, Madrid, Spain

  ⨯
• Belén Iñigo ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Clínico San Carlos, Madrid, Spain

  ⨯
• María del Mar Nieto ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Complejo Hospitalario de Jaén, Jaén, Spain

  ⨯
• Rosa Vidal ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Fundación Jiménez Díaz, Madrid, Spain

  ⨯
• María Paz Martínez ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Nuestra Sra. de Sonsoles, Ávila, Spain

  ⨯
• Reyes Aguinaco ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Joan XXIII, Tarragona, Spain

  ⨯
• Maria Tenorio ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Ramón y Cajal, Madrid, Spain

  ⨯
• María Ferreiro ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Montecelo, Pontevedra, Spain

  ⨯
• Javier García-Frade ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Río Hortega, Valladolid, Spain

  ⨯
• Ana María Rodríguez-Huerta ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Gregorio Marañón, Madrid, Spain

  ⨯
• Jorge Cuesta ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Virgen de la Salud, Toledo, Spain

  ⨯
• Ramón Rodríguez-González ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Severo Ochoa, Madrid, Spain

  ⨯
• Faustino García-Candel ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Universitario Virgen Arrixaca, Murcia, Spain

  ⨯
• Manuela Dobón ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Lozano Blesa, Zaragoza, Spain

  ⨯
• Carlos Aguilar ,

  Roles Resources, Supervision

  ¶‡ These authors also contributed equally to this work.

  Affiliation Servicio Hematología, Hospital Santa Bárbara, Soria, Spain

  ⨯
• Fernando Batlle ,

  Roles Software

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Research, Lapisoft Project S.L., A Coruña, Spain

  ⨯
• Francisco Vidal ,

  Contributed equally to this work with: Almudena Pérez-Rodríguez, Javier Batlle, Irene Corrales, Nina Borràs, Francisco Vidal, María Fernanda López-Fernández

  Roles Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Validation

  Affiliations Banc de Sang i Teixits, Barcelona, Spain, Unitat d’Hemofilia, Vall d’Hebron Research Institute, Universitat Autònoma de Barcelona (VHIR-UAB), Barcelona, Spain, CIBER de Enfermedades Cardiovasculares (CIBERCV), Barcelona, Spain

  http://orcid.org/0000-0001-8089-4945

  ⨯
•  [ ... ],
• María Fernanda López-Fernández

  Contributed equally to this work with: Almudena Pérez-Rodríguez, Javier Batlle, Irene Corrales, Nina Borràs, Francisco Vidal, María Fernanda López-Fernández

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Validation, Writing – original draft

  Affiliation Servicio Hematología, Complexo Hospitalario Universitario A Coruña, INIBIC, A Coruña, Spain

  ⨯
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