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Open Access
Peer-reviewed
Research Article
Impact of LINE-1 hypomethylation on the clinicopathological and molecular features of colorectal cancer patients
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Tai-Chuan Kuan ,
Contributed equally to this work with: Tai-Chuan Kuan, Pei-Ching Lin
Roles Writing – original draft
Affiliations Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Surgery, Faculty of Medicine, School of Medicine, National Yang-Ming University,Taipei, Taiwan
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Pei-Ching Lin ,
Contributed equally to this work with: Tai-Chuan Kuan, Pei-Ching Lin
Roles Conceptualization, Formal analysis
Affiliations Department of Clinical Pathology, Yang-Ming Branch, Taipei City Hospital, Taipei, Taiwan, Department of Health and Welfare, University of Taipei, Taipei, Taiwan
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Shung-Haur Yang,
Roles Data curation, Funding acquisition
Affiliations Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Surgery, Faculty of Medicine, School of Medicine, National Yang-Ming University,Taipei, Taiwan
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Chun-Chi Lin,
Roles Data curation, Validation
Affiliations Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Surgery, Faculty of Medicine, School of Medicine, National Yang-Ming University,Taipei, Taiwan
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Yuan-Tzu Lan,
Roles Data curation, Investigation
Affiliations Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Surgery, Faculty of Medicine, School of Medicine, National Yang-Ming University,Taipei, Taiwan
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Hung-Hsin Lin,
Roles Funding acquisition, Investigation, Methodology
Affiliations Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Surgery, Faculty of Medicine, School of Medicine, National Yang-Ming University,Taipei, Taiwan
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Wen-Yi Liang,
Roles Visualization
Affiliation Department of Pathology, Taipei Veterans General Hospital, Taipei, Taiwan
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Wei-Shone Chen,
Roles Data curation, Investigation, Resources
Affiliations Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Surgery, Faculty of Medicine, School of Medicine, National Yang-Ming University,Taipei, Taiwan
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Jen-Kou Lin,
Roles Resources, Supervision, Validation
Affiliations Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Surgery, Faculty of Medicine, School of Medicine, National Yang-Ming University,Taipei, Taiwan
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Jeng-Kai Jiang ,
Roles Conceptualization, Data curation, Project administration, Supervision
* E-mail: changsc@vghtpe.gov.tw (SCC); jkjiang@vghtpe.gov.tw (JKJ)
Affiliations Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Surgery, Faculty of Medicine, School of Medicine, National Yang-Ming University,Taipei, Taiwan
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Shih-Ching Chang
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – review & editing
* E-mail: changsc@vghtpe.gov.tw (SCC); jkjiang@vghtpe.gov.tw (JKJ)
Affiliations Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Surgery, Faculty of Medicine, School of Medicine, National Yang-Ming University,Taipei, Taiwan
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Impact of LINE-1 hypomethylation on the clinicopathological and molecular features of colorectal cancer patients
- Tai-Chuan Kuan,
- Pei-Ching Lin,
- Shung-Haur Yang,
- Chun-Chi Lin,
- Yuan-Tzu Lan,
- Hung-Hsin Lin,
- Wen-Yi Liang,
- Wei-Shone Chen,
- Jen-Kou Lin,
- Jeng-Kai Jiang
- Published: May 24, 2018
- https://doi.org/10.1371/journal.pone.0197681