Efficacy and safety of direct oral anticoagulants approved for cardiovascular indications: Systematic review and meta-analysis

• Raghavendra Charan P. Makam,

  Roles Conceptualization, Data curation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, United States of America, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America, Division of Cardiac Surgery, Department of Surgery, Johns Hopkins University, Baltimore, MD, United States of America

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• David C. Hoaglin,

  Roles Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, United States of America

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• David D. McManus ,

  Contributed equally to this work with: David D. McManus, Hong Yu, Robert J. Goldberg

  Roles Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America

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• Victoria Wang,

  Roles Formal analysis, Methodology

  Affiliation Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, United States of America

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• Joel M. Gore,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America

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• Frederick A. Spencer,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Medicine, McMaster University, Hamilton, Canada

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• Richeek Pradhan,

  Roles Data curation, Formal analysis

  Affiliation Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, United States of America

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• Hoang Tran,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, United States of America

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• Hong Yu ,

  Contributed equally to this work with: David D. McManus, Hong Yu, Robert J. Goldberg

  Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – review & editing

  Affiliations Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, United States of America, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America, Department of Computer Science, University of Massachusetts, Amherst, MA, United States of America, Center for Healthcare Organization & Implementation Research, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA, United States of America, Department of Computer Science, University of Massachusetts, Lowell, MA, United States of America

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• Robert J. Goldberg

  Contributed equally to this work with: David D. McManus, Hong Yu, Robert J. Goldberg

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: Robert.Goldberg@umassmed.edu

  Affiliation Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, United States of America

  http://orcid.org/0000-0001-7705-7740

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