Increased mitochondrial fission is critical for hypoxia-induced pancreatic beta cell death

Da Zhang; Yanfang Liu; Yao Tang; Xiaofeng Wang; Zhichao Li; Rui Li; Zhenyu Ti; Weidong Gao; Jigang Bai; Yi Lv

doi:10.1371/journal.pone.0197266

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Open Access

Peer-reviewed

Research Article

Increased mitochondrial fission is critical for hypoxia-induced pancreatic beta cell death

Da Zhang,

Roles Project administration, Writing – original draft

Affiliations Department of Hepatobiliary Surgery, Institute of Advanced Surgical Technology and Engineering, Shaanxi Center for Regenerative Medicine and Surgical Engineering, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China, Department of General Surgery, Xi'an No.3 Hospital, Xi’an, China
⨯
Yanfang Liu,

Roles Data curation, Investigation, Project administration

Affiliation Department of Ophthalmology, Xi'an Children’s Hospital,Xi’an, China
⨯
Yao Tang,

Roles Investigation, Resources

Affiliation Department of General Surgery, Xi'an No.3 Hospital, Xi’an, China
⨯
Xiaofeng Wang,

Roles Investigation

Affiliation Department of General Surgery, Xi'an No.3 Hospital, Xi’an, China
⨯
Zhichao Li,

Roles Investigation

Affiliation Department of General Surgery, Xi'an No.3 Hospital, Xi’an, China
⨯
Rui Li,

Roles Investigation

Affiliation Department of General Surgery, Xi'an No.3 Hospital, Xi’an, China
⨯
Zhenyu Ti,

Roles Methodology

Affiliation Department of General Surgery, Xi'an No.3 Hospital, Xi’an, China
⨯
Weidong Gao,

Roles Investigation

Affiliation Department of General Surgery, Xi'an No.3 Hospital, Xi’an, China
⨯
Jigang Bai,

Roles Investigation

Affiliation Department of Hepatobiliary Surgery, Institute of Advanced Surgical Technology and Engineering, Shaanxi Center for Regenerative Medicine and Surgical Engineering, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China
⨯
Yi Lv

Roles Supervision, Writing – review & editing

* E-mail: luyi169@126.com

Affiliation Department of Hepatobiliary Surgery, Institute of Advanced Surgical Technology and Engineering, Shaanxi Center for Regenerative Medicine and Surgical Engineering, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China

http://orcid.org/0000-0002-5821-9270

⨯

Increased mitochondrial fission is critical for hypoxia-induced pancreatic beta cell death

Da Zhang,
Yanfang Liu,
Yao Tang,
Xiaofeng Wang,
Zhichao Li,
Rui Li,
Zhenyu Ti,
Weidong Gao,
Jigang Bai,
Yi Lv

Published: May 16, 2018
https://doi.org/10.1371/journal.pone.0197266

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Mitochondria
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Hypoxia
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Apoptosis
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Cell death
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Medical hypoxia
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Cell fusion
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Transmission electron microscopy
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