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Open Access
Peer-reviewed
Research Article
Generation of hepatocyte- and endocrine pancreatic-like cells from human induced endodermal progenitor cells
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Rangarajan Sambathkumar ,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: Catherine.verfaillie@kuleuven.be (CMV); ranga.1987@hotmail.com (RS)
Current address: Toronto General Hospital Research Institute, McEwen Centre for Regenerative Medicine, University Health Network, Toronto, Ontario, Canada
Affiliation KU Leuven, Interdepartmental Stem Cell Institute, Department of Development and Regeneration, Stem Cell Biology and Embryology, Leuven, Belgium
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Renate Akkerman,
Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization
Affiliations KU Leuven, Interdepartmental Stem Cell Institute, Department of Development and Regeneration, Stem Cell Biology and Embryology, Leuven, Belgium, University of Groningen, University Medical Center Groningen (UMCG), Pathology and Medical Biology, Division of Medical Biology, Section Immunoendocrinology, Groningen, The Netherlands
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Sumitava Dastidar,
Roles Data curation, Formal analysis, Investigation, Methodology
Current address: Free University of Brussels (VUB), Faculty of Medicine & Pharmacy, Department of Gene Therapy & Regenerative Medicine (GTRM), Brussels (Jette campus), Belgium
Affiliation KU Leuven, Interdepartmental Stem Cell Institute, Department of Development and Regeneration, Stem Cell Biology and Embryology, Leuven, Belgium
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Philip Roelandt,
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliation KU Leuven, Interdepartmental Stem Cell Institute, Department of Development and Regeneration, Stem Cell Biology and Embryology, Leuven, Belgium
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Manoj Kumar,
Roles Data curation, Formal analysis, Investigation, Methodology
Affiliation KU Leuven, Interdepartmental Stem Cell Institute, Department of Development and Regeneration, Stem Cell Biology and Embryology, Leuven, Belgium
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Manmohan Bajaj,
Roles Data curation, Formal analysis
Affiliation KU Leuven, Interdepartmental Stem Cell Institute, Department of Development and Regeneration, Stem Cell Biology and Embryology, Leuven, Belgium
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Ana Rita Mestre Rosa,
Roles Data curation, Formal analysis, Investigation, Methodology, Validation
Affiliation KU Leuven, Interdepartmental Stem Cell Institute, Department of Development and Regeneration, Stem Cell Biology and Embryology, Leuven, Belgium
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Nicky Helsen,
Roles Data curation, Formal analysis, Methodology
Affiliation KU Leuven, Interdepartmental Stem Cell Institute, Department of Development and Regeneration, Stem Cell Biology and Embryology, Leuven, Belgium
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Veerle Vanslembrouck,
Roles Data curation, Investigation, Methodology, Validation, Visualization
Affiliation KU Leuven, Interdepartmental Stem Cell Institute, Department of Development and Regeneration, Stem Cell Biology and Embryology, Leuven, Belgium
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Eric Kalo,
Roles Data curation, Formal analysis, Investigation
Affiliation KU Leuven, Interdepartmental Stem Cell Institute, Department of Development and Regeneration, Stem Cell Biology and Embryology, Leuven, Belgium
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Satish Khurana,
Roles Data curation, Formal analysis, Methodology
Affiliation School of Biology, Indian Institute of Science Education and Research, Thiruvananthapuram, Kerala, India
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Jos Laureys,
Roles Investigation, Methodology
Affiliation KU Leuven, Department of Clinical and Experimental Medicine, Clinical and Experimental Endocrinology unit, Leuven, Belgium
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Conny Gysemans,
Roles Investigation, Methodology
Affiliation KU Leuven, Department of Clinical and Experimental Medicine, Clinical and Experimental Endocrinology unit, Leuven, Belgium
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Marijke M. Faas,
Roles Funding acquisition, Project administration, Supervision, Writing – review & editing
Affiliations University of Groningen, University Medical Center Groningen (UMCG), Pathology and Medical Biology, Division of Medical Biology, Section Immunoendocrinology, Groningen, The Netherlands, University of Groningen, University Medical Center Groningen (UMCG), Department of Obstetrics and Gynecology, Groningen, The Netherlands
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Paul de Vos,
Roles Funding acquisition, Project administration, Supervision, Writing – review & editing
Affiliation University of Groningen, University Medical Center Groningen (UMCG), Pathology and Medical Biology, Division of Medical Biology, Section Immunoendocrinology, Groningen, The Netherlands
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Catherine M. Verfaillie
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: Catherine.verfaillie@kuleuven.be (CMV); ranga.1987@hotmail.com (RS)
Affiliation KU Leuven, Interdepartmental Stem Cell Institute, Department of Development and Regeneration, Stem Cell Biology and Embryology, Leuven, Belgium
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Generation of hepatocyte- and endocrine pancreatic-like cells from human induced endodermal progenitor cells
- Rangarajan Sambathkumar,
- Renate Akkerman,
- Sumitava Dastidar,
- Philip Roelandt,
- Manoj Kumar,
- Manmohan Bajaj,
- Ana Rita Mestre Rosa,
- Nicky Helsen,
- Veerle Vanslembrouck,
- Eric Kalo
- Published: May 11, 2018
- https://doi.org/10.1371/journal.pone.0197046