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Open Access
Peer-reviewed
Research Article
Endothelium-targeted delivery of dexamethasone by anti-VCAM-1 SAINT-O-Somes in mouse endotoxemia
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Ranran Li,
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing
Affiliation Dept. of Pathology & Medical Biology, Medical Biology Section, Laboratory for Endothelial Biomedicine & Vascular Drug Targeting Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Piotr S. Kowalski,
Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing
Affiliation Dept. of Pathology & Medical Biology, Medical Biology Section, Laboratory for Endothelial Biomedicine & Vascular Drug Targeting Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Henriëtte W. M. Morselt,
Roles Investigation, Writing – review & editing
Affiliation Dept. of Pathology & Medical Biology, Medical Biology Section, Laboratory for Endothelial Biomedicine & Vascular Drug Targeting Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Ilona Schepel,
Roles Investigation, Writing – review & editing
Affiliation Dept. of Pathology & Medical Biology, Medical Biology Section, Laboratory for Endothelial Biomedicine & Vascular Drug Targeting Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Rianne M. Jongman,
Roles Investigation, Writing – review & editing
Affiliations Dept. of Pathology & Medical Biology, Medical Biology Section, Laboratory for Endothelial Biomedicine & Vascular Drug Targeting Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Dept. of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Dept. of Anesthesiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Adnan Aslan,
Roles Investigation, Writing – review & editing
Affiliations Dept. of Pathology & Medical Biology, Medical Biology Section, Laboratory for Endothelial Biomedicine & Vascular Drug Targeting Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Dept. of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Marcel H. J. Ruiters,
Roles Investigation, Resources, Writing – review & editing
Affiliation Dept. of Pathology & Medical Biology, Medical Biology Section, Laboratory for Endothelial Biomedicine & Vascular Drug Targeting Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Jan G. Zijlstra,
Roles Conceptualization, Writing – review & editing
Affiliation Dept. of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Grietje Molema,
Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing
Affiliation Dept. of Pathology & Medical Biology, Medical Biology Section, Laboratory for Endothelial Biomedicine & Vascular Drug Targeting Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Matijs van Meurs,
Roles Conceptualization, Formal analysis, Investigation, Supervision, Writing – review & editing
Affiliations Dept. of Pathology & Medical Biology, Medical Biology Section, Laboratory for Endothelial Biomedicine & Vascular Drug Targeting Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Dept. of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Jan A. A. M. Kamps
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – review & editing
* E-mail: j.a.a.m.kamps@umcg.nl
Affiliation Dept. of Pathology & Medical Biology, Medical Biology Section, Laboratory for Endothelial Biomedicine & Vascular Drug Targeting Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Endothelium-targeted delivery of dexamethasone by anti-VCAM-1 SAINT-O-Somes in mouse endotoxemia
- Ranran Li,
- Piotr S. Kowalski,
- Henriëtte W. M. Morselt,
- Ilona Schepel,
- Rianne M. Jongman,
- Adnan Aslan,
- Marcel H. J. Ruiters,
- Jan G. Zijlstra,
- Grietje Molema,
- Matijs van Meurs
- Published: May 15, 2018
- https://doi.org/10.1371/journal.pone.0196976