Tauroursodeoxycholic acid (TUDCA) alleviates endoplasmic reticulum stress of nuclear donor cells under serum starvation

Ying Zhang; Pengxiang Qu; Xiaonan Ma; Fang Qiao; Yefei Ma; Suzhu Qing; Yong Zhang; Yongsheng Wang; Wei Cui

doi:10.1371/journal.pone.0196785

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Peer-reviewed

Research Article

Tauroursodeoxycholic acid (TUDCA) alleviates endoplasmic reticulum stress of nuclear donor cells under serum starvation

Ying Zhang,

Roles Data curation, Formal analysis, Investigation, Validation, Writing – original draft, Writing – review & editing

Affiliations Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, PR China, Engineering Center for Animal Embryo Technology, Yangling, Shaanxi, PR China, Laboratory of Embryo Technology in Livestock, Northwest A&F University, Yangling, Shaanxi, PR China
⨯
Pengxiang Qu,

Roles Data curation, Formal analysis, Investigation, Validation, Writing – original draft, Writing – review & editing

Affiliations Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, PR China, Engineering Center for Animal Embryo Technology, Yangling, Shaanxi, PR China, Laboratory of Embryo Technology in Livestock, Northwest A&F University, Yangling, Shaanxi, PR China
⨯
Xiaonan Ma,

Roles Investigation

Affiliations Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, PR China, Engineering Center for Animal Embryo Technology, Yangling, Shaanxi, PR China, Laboratory of Embryo Technology in Livestock, Northwest A&F University, Yangling, Shaanxi, PR China
⨯
Fang Qiao,

Roles Investigation

Affiliations Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, PR China, Engineering Center for Animal Embryo Technology, Yangling, Shaanxi, PR China, Laboratory of Embryo Technology in Livestock, Northwest A&F University, Yangling, Shaanxi, PR China
⨯
Yefei Ma,

Roles Investigation

Affiliation Department of Gynecology and Obstetrics, Tangdu Hospital, the Fourth Military Medical University, Xi'an, Shannxi Province, PR China
⨯
Suzhu Qing,

Roles Investigation

Affiliations Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, PR China, Engineering Center for Animal Embryo Technology, Yangling, Shaanxi, PR China, Laboratory of Embryo Technology in Livestock, Northwest A&F University, Yangling, Shaanxi, PR China
⨯
Yong Zhang ,

Roles Conceptualization, Resources

* E-mail: Zhangyong1956110@163.com (YZ); wangyongsheng01@nwsuaf.edu.cn (YW); wcui@umass.edu (WC)

Affiliations Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, PR China, Engineering Center for Animal Embryo Technology, Yangling, Shaanxi, PR China, Laboratory of Embryo Technology in Livestock, Northwest A&F University, Yangling, Shaanxi, PR China
⨯
Yongsheng Wang ,

Roles Conceptualization, Data curation, Formal analysis, Resources, Validation, Writing – original draft, Writing – review & editing

* E-mail: Zhangyong1956110@163.com (YZ); wangyongsheng01@nwsuaf.edu.cn (YW); wcui@umass.edu (WC)

Affiliations Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, PR China, Engineering Center for Animal Embryo Technology, Yangling, Shaanxi, PR China, Laboratory of Embryo Technology in Livestock, Northwest A&F University, Yangling, Shaanxi, PR China
⨯
Wei Cui

Roles Conceptualization, Formal analysis, Resources, Writing – original draft, Writing – review & editing

* E-mail: Zhangyong1956110@163.com (YZ); wangyongsheng01@nwsuaf.edu.cn (YW); wcui@umass.edu (WC)

Affiliations Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA, United States of America, Animal Models Core Facility, Institute for Applied Life Sciences (IALS), University of Massachusetts, Amherst, MA, United States of America

http://orcid.org/0000-0001-7281-3471

⨯

Tauroursodeoxycholic acid (TUDCA) alleviates endoplasmic reticulum stress of nuclear donor cells under serum starvation

Ying Zhang,
Pengxiang Qu,
Xiaonan Ma,
Fang Qiao,
Yefei Ma,
Suzhu Qing,
Yong Zhang,
Yongsheng Wang,
Wei Cui

Published: May 2, 2018
https://doi.org/10.1371/journal.pone.0196785

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