Molecular structures of cdc2-like kinases in complex with a new inhibitor chemotype

• Anne Walter ,

  Contributed equally to this work with: Anne Walter, Apirat Chaikuad

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Software, Visualization, Writing – original draft

  Affiliations Institut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, Braunschweig, Germany, Center of Pharmaceutical Engeneering (PVZ), Technische Universität Braunschweig, Braunschweig, Germany

  ⨯
• Apirat Chaikuad ,

  Contributed equally to this work with: Anne Walter, Apirat Chaikuad

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Writing – review & editing

  Affiliations Structural Genomics Consortium, Nuffield Department of Medicine, Oxford University, Oxford, United Kingdom, Institute for Pharmaceutical Chemistry, Structural Genomics Consortium and Buchmann Institute for Molecular Life Sciences, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany

  ⨯
• Renate Helmer,

  Roles Data curation, Investigation, Methodology

  Affiliation Institut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, Braunschweig, Germany

  ⨯
• Nadège Loaëc,

  Roles Data curation, Formal analysis, Investigation

  Affiliation ManRos Therapeutics, Hôtel de Recherche, Centre de Perharidy, Roscoff, France

  ⨯
• Lutz Preu,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation Institut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, Braunschweig, Germany

  ⨯
• Ingo Ott,

  Roles Data curation, Formal analysis, Validation, Writing – review & editing

  Affiliations Institut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, Braunschweig, Germany, Center of Pharmaceutical Engeneering (PVZ), Technische Universität Braunschweig, Braunschweig, Germany

  ⨯
• Stefan Knapp,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Writing – review & editing

  Affiliations Structural Genomics Consortium, Nuffield Department of Medicine, Oxford University, Oxford, United Kingdom, Institute for Pharmaceutical Chemistry, Structural Genomics Consortium and Buchmann Institute for Molecular Life Sciences, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany

  ⨯
• Laurent Meijer ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: c.kunick@tu-braunschweig.de (CK); meijer@manros-therapeutics.com (LM)

  Affiliation ManRos Therapeutics, Hôtel de Recherche, Centre de Perharidy, Roscoff, France

  ⨯
• Conrad Kunick

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft

  * E-mail: c.kunick@tu-braunschweig.de (CK); meijer@manros-therapeutics.com (LM)

  Affiliations Institut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, Braunschweig, Germany, Center of Pharmaceutical Engeneering (PVZ), Technische Universität Braunschweig, Braunschweig, Germany

  http://orcid.org/0000-0001-7041-5322

  ⨯